Sökning: "Statin treatment and beta-Amyloid Production in Patients with Alzheimer s Disease"

Hittade 1 avhandling innehållade orden Statin treatment and beta-Amyloid Production in Patients with Alzheimer s Disease.

  1. 1. Statin treatment and beta-Amyloid Production in Patients with Alzheimer s Disease

    Författare :Kina Höglund; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :Alzheimer s disease; amyloid precursor protein; beta-amyloid; cholesterol; statins; CSF;

    Sammanfattning : Alzheimer s disease (AD) is a progressive neurodegenerative disorder pathologically characterized by neurofibrillary tangles and amyloid plaques. According to the amyloid cascade hypothesis, the increased production of beta-amyloid (Abeta), derived form the amyloid precursor protein (APP), and its aggregation into plaques are key pathological events, driving neurodegeneration in AD. LÄS MER