Sökning: "Stanley Rehn"

Hittade 1 avhandling innehållade orden Stanley Rehn.

1. 1. Synthesis of indole and oxindole derivates incorporating pyrrolidino, pyrrolo or imidazolo moieties

   Författare :Stanley Rehn; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Isatin; three-component reaction; a-amino acid; azomethine ylide; pyrrolidino-3-spiro-3?-oxindole derivatives; 3-methyleneoxindole derivatives; pyrroloquinolone; TosMIC; ß-carboline; tosylimine; pyrrole; keto-enol tautomerism; indolopyran-2-one; imidazole; benzylimine; tetrahydroindole;

   Sammanfattning : The focus of this thesis is on the synthesis of oxindole- and indole-derivatives incorporating pyrrolidins, pyrroles or imidazoles moieties. Pyrrolidino-2-spiro-3'-oxindole derivatives have been prepared in high yielding three-component reactions between isatin, alpha-amino acid derivatives, and suitable dipolarophiles. LÄS MER