Sökning: "Stanley Maloy"

Hittade 3 avhandlingar innehållade orden Stanley Maloy.

  1. 1. Genetics and Growth Regulation in Salmonella enterica

    Författare :Jessica M. Bergman; Diarmaid Hughes; Dan I. Andersson; Måns Ehrenberg; Stanley Maloy; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tufA; tufB; EF-Tu; ppGpp; Stringent response; RNase E; RNA turnover; Post-transcriptional regulation; rpoB; rpoS; Growth in stationary phase; Biology with specialization in Microbiology; Biologi med inriktning mot mikrobiologi; Mikrobiologi; Microbiology; Molekylär genetik; Molecular Genetics; Biology with specialization in Molecular Evolution; Biologi med inriktning mot molekylär evolution;

    Sammanfattning : Most free-living bacteria will encounter different environments and it is therefore critical to be able to rapidly adjust to new growth conditions in order to be competitively successful. Responding to changes requires efficient gene regulation in terms of transcription, RNA stability, translation and post-translational modifications. LÄS MER

  3. 2. Experimental Evolution : and Fitness Effects of Mutations

    Författare :Anna Knöppel; Dan I Andersson; Stanley Maloy; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Experimental evolution; Fitness effects; mutations; S20; fis; ribosome; horizontal gene transfer; adaptation; synonymous mutations; Mikrobiologi; Microbiology;

    Sammanfattning : Bacteria have small, streamlined genomes and evolve rapidly. Their large population sizes allow selection to be the main driver of evolution. With advances in sequencing technologies and precise methods for genetic engineering, many bacteria are excellent models for studying elementary questions in evolutionary biology. LÄS MER

  4. 3. The Physiological Cost of Antibiotic Resistance

    Författare :Mirjana Macvanin; Diarmaid Hughes; Stanley Maloy; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; fusidic acid; fitness cost; protein synthesis; EF-G; ppGpp; RpoS; oxidative stress; heme; Mikrobiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar;

    Sammanfattning : Becoming antibiotic resistant is often associated with fitness costs for the resistant bacteria. This is seen as a loss of competitiveness against the antibiotic-sensitive wild-type in an antibiotic-free environment. LÄS MER