Sökning: "Sprague-Dawley"
Visar resultat 6 - 10 av 77 avhandlingar innehållade ordet Sprague-Dawley.
6. Modelling depression in animals and the potential antidepressant effect of histaminergic modulation
Sammanfattning : Depression is at the top position for "years lived with disability" (Smith, 2014). Its aetiology is unknown, but the pathogenesis implicates changes in glutamatergic neuronal plasticity. Glutamatergic plasticity likely mediates the effects of antidepressants acting through monoamines. LÄS MER
7. The effect of caloric restriction on age-related hearing loss and the impact of repeated sound exposures
Sammanfattning : The auditory system is the sensory system responsible for hearing and crucial for communication between individuals. While aging, many organs of the body start losing their function, including the hearing organ. The severity of age-related hearing loss depends on numerous factors. LÄS MER
8. On antidepressant effects of running and SSRI : focus on hippocampus and striatal dopamine pathways
Sammanfattning : Considering the heterogeneous character of depression, it seems likely that many brain regions are involved mediating the diverse symptoms of depression. For example, the mesolimbic DA system has a central function for motivational behaviors and pleasure seeking, and it is possible that malfunctioning of brain reward systems could be an underlying mechanism of the anhedonia experienced in depressive illness. LÄS MER
9. Theranostics in radiology : development of targeted contrast media with treatment capability
Sammanfattning : Imaging is essential in the diagnostics and medicine of today. The development of new contrast agents is important for obtaining specific information from images and to distinguish disease. Microbubbles (MB) have previously been introduced as a contrast agent for ultrasound. LÄS MER
10. Gastric Inhibitory Polypeptide in the brain
Sammanfattning : The hippocampus is an area of active cell proliferation and neurogenesis within the adult mammalian brain. Adult neurogenesis is of great importance for the brain, since it increases neuroplasticity and the ability to respond to environmental stimuli. LÄS MER