Sökning: "Spiral ganglion"

Visar resultat 1 - 5 av 16 avhandlingar innehållade orden Spiral ganglion.

  1. 1. The Human Spiral Ganglion

    Författare :Sven Tylstedt; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Otorhinolaryngology; human spiral ganglion; ultrastructural morphology; neural interaction; synaptophysin; connexin; membrane specializations; synapse; gap junction; tight junction; Otorhinolaryngologi; Otorhinolaryngology; Otorhinolaryngologi; Oto-Rhino-Laryngology; oto-rhino-laryngologi;

    Sammanfattning : Our knowledge of the fine structure of the Human Spiral Ganglion (HSG) is still inadequate and new treatment techniques for deafness using electric stimulation, call for further information and studies on the neuronal elements of the human cochlea. This thesis presents results of analyses of human cochlear tissue and specimens obtained during neurosurgical transpetrosal removal of life-threatening meningeomas. LÄS MER

  3. 2. The molecular basis of spiral ganglion neurons : diversity and development

    Författare :Charles Petitpre; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hearing, one of our main senses, allows us to socialize, listen and enjoy sounds around us. The critical transmitters of the sound information are the spiral ganglion neurons (SGNs); located in the cochlea, they transmit the auditory signals from the hair cells to the brain. LÄS MER

  4. 3. Strategies in Cochlear Nerve Regeneration, Guidance and Protection : Prospects for Future Cochlear Implants

    Författare :Fredrik Edin; Helge Rask-Andersen; Peetra Magnusson; Maoli Duan; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human vestibular nerve; Scarpa s ganglion; Stem cells; Nanoparticles; Nanocrystalline diamond; Oto-Rhino-Laryngology; Oto-rhino-laryngologi; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Today, it is possible to restore hearing in congenitally deaf children and severely hearing-impaired adults through cochlear implants (CIs). A CI consists of an external sound processor that provides acoustically induced signals to an internal receiver. LÄS MER

  5. 4. Modulation of the HPA axis alters the sensitivity of the cochlea to acoustic trauma

    Författare :Yeasmin Tahera; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HPA axis; corticosterone; glucocorticoid receptor; NFêB; spiral ganglion neurons; cochlea; acoustic trauma; paraventricular nucleus;

    Sammanfattning : The hypothalamic pituitary adrenal axis (HPA axis) regulates nearly all neuroendocrine responses of the body. An active HPA axis is crucial to maintaining homeostasis. An altered reactivity of the HPA axis can affect several physiological systems including the auditory system. LÄS MER

  7. 5. Investigating a cell replacement therapy in the inner ear

    Författare :Zhengqing Hu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adult neural stem cell; Cell therapy; Differentiation; Dorsal root ganglion; Embryonic stem cell; Gene transfer; Hearing loss; Nerve growth factor; Neurogenin; Organ of Corti; Spiral ganglion; Transplantation;

    Sammanfattning : The mammalian auditory system is sensitive to genetic disorders, aging and injuries caused by overstimulation, ototoxic drugs and viral infections. Since the sensory epithelium (the organ of Corti) and the spiral ganglion neurons (SGNs) in adult mammalian do not regenerate spontaneously when they are damaged, a cell substitution strategy was proposed to compensate the function of the degenerated SGNs. LÄS MER