Sökning: "Spinal cord injury"

Visar resultat 11 - 15 av 170 avhandlingar innehållade orden Spinal cord injury.

1. 11. A regeneration strategy for spinal cord injury

   Författare :Jonathan Nordblom; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : A severe traumatic spinal cord injury (SCI) frequently leads to a devastating and permanent disability. Due to glial scarring and an inhibitory local environment, regrowth of disrupted axons in the injured spinal cord beyond a lesion is obstructed, thus preventing reconnection with neurons at the other side. LÄS MER

3. 12. Generation of functional neural progenitors for spinal cord transplantation

   Författare :Jan Hoeber; Elena Kozlova; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regenerative Neurobiology; Stem cells; Sensory regeneration; Spinal cord injury; Neuroscience; Neurovetenskap;

   Sammanfattning : Dorsal root avulsion injuries result in permanent impairment of sensory functions due to the disconnection of the peripheral nervous system from the spinal cord. Strategies aiming for the functional reconnection of sensory neurons with their targets in the spinal cord dorsal horn need to overcome the axonal growth non-permissive glial scar and provide a growth promoting environment. LÄS MER

4. 13. Assessment of rat spinal cord injury models

   Författare :Ning Xu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Traumatic spinal cord injury (SCI) is a complicated and devastating condition, causing different extents of motor, sensory and autonomic dysfunctions. In addition, there is a risk for secondary complications after SCI including posttraumatic syringomyelia (PTS) that can cause further functional loss. LÄS MER

5. 14. Human spinal cord models for development of spinal cord injury repair strategies

   Författare :Chenhong Lin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : There is still no available cure for human spinal cord injury (SCI). After a SCI, neural cell loss, excitotoxicity, neuroinflammation, astrocytic and oligodendrocytic derived inhibiting factors contribute to a non-permissive spinal cord environment hindering neuroregeneration with little, if any, endogeneous functional improvement. LÄS MER

7. 15. Autonomic function and myocardial repolarisation. Studies in renal diseases and in spinal cord injury

   Författare :Sinsia Gao; Göteborgs universitet; []
   Nyckelord :vagus; sympathetic nervous system; repolarisation; baroreflex; reproducibility; agreement; hypertension; spinal cord injury; autonomic dysreflexia; renal failure.;

   Sammanfattning : Both experimental and clinical evidence indicates that cardiac parasympathetic markers such as baroreflex sensitivity (BRS) and heart rate variability (HRV) have significant prognostic value. Furthermore, increased myocardial repolarisation lability reflected by increased QT variability index (QTVI) has been identified as a predictor for sudden cardiac death. LÄS MER