Sökning: "Sperm chromatin"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden Sperm chromatin.

  1. 1. Chromatin and transcriptome-based integrative approaches to profile functional long noncoding RNAs - A computational approach

    Författare :Santhilal Subhash; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Computational biology; Long noncoding RNAs; Chromatin; S-phase; Cell cycle; sperm; Epigenetics; Histone; cancer; oncogene; Tumor suppressor; DNA methylation; Histone modifications; Chromatin remodelers; lncRNAs; lincRNAs;

    Sammanfattning : One of the major hallmarks of cancer is aberrant or uncontrollable cell division, which occurs due to a defective cell cycle process. During the synthesis phase (S-phase) of the cell cycle, before cell division or mitosis phase, the DNA in the cell makes a new copy to pass on genetic information to the daughter cells. LÄS MER

  3. 2. Zinc and human sperm chromatin

    Författare :Svante Kjellberg; Björn Afzelius; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : X-rny microanalysis, Sephadex® chromatography of seminal plasma and exposure of spermatozoa to sodium dodecyl sulphate (SDS), were methods used to study the zinc content of sperm chromatin, the nature of the zinc binding ligands present in seminal plasma and the stability of the sperm chromatin in whole semen samples from fertile and infertile men. Split ejaculates were used to study the same variables in different fractions of the same ejaculate. LÄS MER

  4. 3. EXPOSURE TO PERSISTENT ORGANOCHLORINE POLLUTANTS AND MALE SEMEN FUNCTION

    Författare :Anna Rignell-Hydbom; Avdelningen för arbets- och miljömedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Miljömedicin; Environmental health; epididymal and accessory sex gland function; Y:X sperm chromosome ratio; sperm chromation integrity; sperm concentration; sperm motility; persistent organochlorine poluutants;

    Sammanfattning : Persistent organochlorine pollutants (POPs), such as polychlorinated biphenyls (PCB) and the insecticide dichloro-diphenyl-dichloro-ethylene (DDT) have been released into the environment mainly since the second World War. POPs accumulate especially in highly ranked predators of the aquatic food chain. LÄS MER

  5. 4. Studies on genetic aberrations as possible predictors of the outcome of assisted reproduction

    Författare :Mona Bungum; Malmö Reproduktionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; assisted reproduction; IUI; Sperm chromatin; ICSI; intra-individual variation; fertilisation failure genetic aberration; Protein C inhibitor gene; sperm DNA damage SCSA; IVF;

    Sammanfattning : Traditionally, diagnosis of male infertility has relied upon microscopic assessment of semen. The normality criteria set by the World Health Organization (WHO) in regard to sperm concentration, motility and morphology are, however, poor predictors of fertility. LÄS MER

  7. 5. Sperm DNA Fragmentation - Infertility treatment, pregnancy, and the risk of congenital malformations

    Författare :Amelie Stenqvist; Malmö Reproduktionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infertility; Sperm DNA fragmentation; in vitro fertilization; sperm chromatin structure assay SCSA ; cumulative live birth rate; preeclampsia; preterm birth; congenital malformations;

    Sammanfattning : .... LÄS MER