Sökning: "Sp3"

Visar resultat 1 - 5 av 34 avhandlingar innehållade ordet Sp3.

  1. 1. Transcription factors regulating the Btk promoter

    Författare :Susanne Müller; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Btk; X-linked agammaglobulinemia; transcription factors; repression; synergism; Sp 1; Sp3; PU.l; Spi-B; genetherapy.;

    Sammanfattning : Bruton's agammaglobulinemia tyrosine kinase (Btk) is a cytoplasmic tyrosine kinase-related to the Src family of kinases. Mutations in various parts of the gene have been shown to lead to X-linked agammaglobulinemia, an immunodeficiency disease which is characterized by a defect in B-cell development. LÄS MER

  2. 2. Nickel and iridium pincer complexes with saturated frameworks - synthesis and reactivity

    Författare :Klara Jonasson; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PCP complexes; aliphatic pincer ligands; coordination; cyclometallation; iridium; nickel; organometallic synthesis; CO2 activation; catalysis;

    Sammanfattning : As the tridentate chelate complexes referred to as pincer complexes have expanded their scope as homogeneous catalysts, there is an increased interest in electronic and steric fine-tuning of such complexes. One accessible variable in this aspect is the hybridisation of any coordinated carbon atoms. LÄS MER

  3. 3. Transcriptional regulation of genes expressed in the parathyroid gland

    Författare :Anders Knutson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : A dynamic interplay between promoter sequences and transcription factors ensures that genes are expressed at appropriate levels in each cell throughout the body. In the present investigation, the promoters of two different genes encoding proteins involved in parathyroid cell function and calcium homeostasis were studied. LÄS MER

  4. 4. New Reactions with Allyl- and Allenylboron Reagents : Transition-Metal-Catalyzed and Transition-Metal-Free Carbon-Carbon Bond Formation Processes

    Författare :Dong Wang; Kálmán J. Szabó; Jianbo Wang; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; carbon-carbon bond formation; cross-coupling; organoboron compound; allylboron reagent; allylation; transition metal; metal carbene; allenylboron reagent; transition metal free; diazo compound; tosylhydrazone; quinone; organisk kemi; Organic Chemistry;

    Sammanfattning : Organoboron compounds have been widely used in carbon-carbon bond formation reactions in organic synthesis and catalysis. This thesis is focused on cross-coupling reactions of allyl-, allenylboronic acids and their ester derivatives via transition metal catalysis or transition-metal-free processes. LÄS MER

  5. 5. Properties of Fe/ZnSe Heterostructures : A Step Towards Semiconductor Spintronics

    Författare :Fredrik Gustavsson; Poul Erik Lindelof; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physics; semiconductor spintronics Fe ZnSe heterostructures spin injection interface magnetism magnetic tunnel junctions; Fysik; Physics; Fysik; Fysik; Physics;

    Sammanfattning : In the present thesis, the properties at ferromagnet/semiconductor interfaces, relevant for semiconductor spintronics applications, are addressed. Semiconductor spintronics refers to the possibility of storing information using the electron spin, additional to the electron charge, for enhanced flexibility in nanoscale semiconductor devices. LÄS MER