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  1. 1. Proteasome Inhibitors against Cancer: Determining Biology and Finding Novel Compounds

    Författare :Arjan Mofers; Stig Linder; Padraig D´arcy; Sonia Lain; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Cancer continues to be a tremendous burden on society in terms of loss of quality of life and life-years. The ubiquitin proteasome system (UPS), responsible for the bulk of protein turnover in the cell, is considered an attractive target in cancer therapy. LÄS MER