Sökning: "Solute transport"

Visar resultat 6 - 10 av 91 avhandlingar innehållade orden Solute transport.

  1. 6. Atypical Solute Carriers : Identification, evolutionary conservation, structure and histology of novel membrane-bound transporters

    Författare :Emelie Perland; Robert Fredriksson; Helgi Schiöth; Åsa Mackenzie; Sonchita Bagchi; Carsten Uhd Nielsen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Major facilitator superfamily; solute carrier; transporter; protein expression; mRNA expression; phylogenetic clustering; orthologues; co-expression; subcellular location; nutrition.; Neuroscience; Neurovetenskap;

    Sammanfattning : Solute carriers (SLCs) constitute the largest family of membrane-bound transporter proteins in humans, and they convey transport of nutrients, ions, drugs and waste over cellular membranes via facilitative diffusion, co-transport or exchange. Several SLCs are associated with diseases and their location in membranes and specific substrate transport makes them excellent as drug targets. LÄS MER

  3. 7. Solute Carriers in Metabolism : Regulation of known and putative solute carriers in the central nervous system

    Författare :Emilia Lekholm; Robert Fredriksson; Helgi B. Schiöth; David Drew; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Solute Carriers; transporter; amino acid starvation; glucose metabolism; MFS; SV2; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Solute carriers (SLCs) are membrane-bound transporter proteins, important for nutrient, ion, drug and metabolite transport across membranes. A quarter of the human genome codes for membrane-bound proteins, and SLCs make up the largest group of transporter proteins. LÄS MER

  4. 8. The influence of multiscale hyporheic flow on solute transport : Implications for stream restoration enhancing nitrogen removal

    Författare :Ida Morén; Anders Wörman; Joakim Riml; Roy Haggerty; KTH; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Hyporheic exchange flow; Hydrological modeling; Solute transport; Stream restoration; Nitrogen; Power spectral analysis; Hydraulic and Hydrologic Engineering; Hydraulik och teknisk hydrologi;

    Sammanfattning : Stream water that flows into and out of streambeds is called hyporheic exchange flow (HEF).It continuously interacts with groundwater and thereby affect the water quality of local streamreaches as well as downstream recipients by providing an environment where solutes andenergy can be retained and degraded. LÄS MER

  5. 9. Solute Transport in Fractured Rocks : The Effect of Stagnant Water Zones and Velocity Dispersion

    Författare :Pirouz Shahkarami; Longcheng Liu; Ivars Neretnieks; Luis Moreno; Klaus-Peter Kröhn; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Channel network concept; radionuclide transport; stagnant water zones; velocity dispersion; modeling and simulation; Chemical Engineering; Kemiteknik;

    Sammanfattning : The focus of this thesis is on the development of new models to improve our understanding of radionuclide transport in the repository “far-field” in fractured rocks. The proposed models contribute to the channel network concept and describe the recently developed models with stagnant water zones (STWZs) and channels with variable aperture allowing to consider their possible impacts on the overall transport of radionuclides in fractured rocks. LÄS MER

  7. 10. Solute transport through fractured rocks : the influence of geological heterogeneities and stagnant water zones

    Författare :Batoul Mahmoudzadeh; Longcheng Liu; Ivars Neretnieks; David Hodgkinson; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : To describe reactive solute transport and retardation through fractured rocks, three models are developed in the study with different focuses on the physical processes involved and different simplifications of the basic building block of the heterogeneous rock domain. The first model evaluates the effects of the heterogeneity of the rock matrix and the stagnant water zones in part of the fracture plane. LÄS MER