Sökning: "Smoking induced disease"

Visar resultat 21 - 25 av 44 avhandlingar innehållade orden Smoking induced disease.

  1. 21. Smoking and human airway inflammatory cells : studies with focus on T cells in the development of COPD

    Författare :Helena Forsslund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic obstructive pulmonary disease (COPD), the fourth leading cause of death worldwide, is characterized by persistent airflow limitation and a chronic inflammation of the lungs. One of the major risk factors is long-term exposure to cigarette smoking. LÄS MER

  2. 22. Stress Response in Chronic Obstructive Pulmonary Disease - Effect of Cigarette Smoke Extract and Hypoxia on Structural Lung Cells

    Författare :Martin Garcia-Ryde; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; COPD; Cigarette smoke extract CSE ; Lung fibroblasts; Hypoxia; Gene expression;

    Sammanfattning : Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide according to the world health organization. It is a disease characterized by chronic inflammation and emphysema, and cigarette smoking is the main cause of COPD development. LÄS MER

  3. 23. Hyperreactive peripheral neutrophils in periodontitis : FCc receptor activation and plasma proteins

    Författare :Margareta Fredriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Periodontitis neutrophils; oxygen radicals; smoking; priming.;

    Sammanfattning : It is now well established that adult and juvenile periodontitis are associated with a hyperreactivity of the peripheral neutrophils when measured as increased generation of free oxygen radicals after stimulation of the Fcgamma-receptors. Aim: The aims of these investigations were to study if the increased radical generation was: 1) located intra- or extracellularly and attributed to a specific oxygen species or various activation pathways, 2) connected with "priming" (pre-stimulation only disclosed by a secondary activation), 3) associated with systemic aberrations in plasma parameters induced by the periodontal disease or cigarette smoking or 4) related to the neutrophil production of the cytokines IL-8 and TNFalpha after stimulation. LÄS MER

  4. 24. Factors affecting peri-implant tissue reactions

    Författare :Margareta Hultin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Dental implants long-term maintenance; microbiota; inflammation; periodontitis; periimplantitis smoking crevicular fluid.;

    Sammanfattning : Screw- shaped titanium implants are today routinely used m the substitution of lost teeth. In this thesis some of the biological factors related to the long-term survival and maintenance of dental implants were studied. The first arm of these studies was to evaluate the neutrophil activation around teeth and dental implants (Papers I & II). LÄS MER

  5. 25. Anxiety, exhaustion and depression in relation to periodontal diseases

    Författare :Annsofi Johannsen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Anxiety; stress; depression; gingival inflammation; periodontal diseases; smoking; inflammatory markers; cortisol; HPA axis;

    Sammanfattning : Periodontal diseases (gingivitis and periodontitis), are inflammatory processes of the gingiva and supporting structures of the teeth induced by a microbial biofilm. In periodontitis this inflammatory process causes tissue degradation and eventually tooths loss. LÄS MER