Sökning: "Skinned fibers"

Hittade 2 avhandlingar innehållade orden Skinned fibers.

  1. 1. The role of exercise and exercise-related factors in the control of mitochondrial oxidative function

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Physiology and Pharmacology

    Författare :Brandon Walsh; Karolinska Institutet.; Karolinska Institutet.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skinned fibers; permeabilized fibers; skeletal muscle; exercise; mitochondria; ADP sensitivity; aerobic metabolism; training; eccentric; high intensity; creatine; phosphocreatine; inorganic phosphate; hydrogen ions;

    Sammanfattning : The effects of exercise and exercise-related factors on the control of mitochondrial oxidative function were investigated in human and rat skeletal muscle. Oxidative function was assessed through the measurement of oxygen consumption in chemically permeabilized (skinned) fibers. LÄS MER

  2. 2. Adaptability of skeletal muscle to hormone treatment in relation to gender and aging

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Clinical Neuroscience

    Författare :Fushun Yu; Karolinska Institutet.; Karolinska Institutet.; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; skinned muscle fiber; gender; aging; steroid hormone; V0 electrophoresis; MyHC; MyLC; enzymehistochemistry; hyperthyroid rat; thyroid hormone receptor TR deficient TR[alpha]1 - -; TR[beta]- -; and TR[alpha]1- -[beta]- - mice;

    Sammanfattning : The aims of this study were to investigate the expression of myosin isoforms, muscle contractility at the cell level, and changes in these parameters in response to altered hormonal status in aging male and female rodents. In addition, by using mice lacking thyroid hormone receptors (TR[alpha]1 or TR[beta] or TR[alpha]1/[beta]) we tried to improve our understanding of the mechanisms by which thyroid hormone regulates the expression of specific MyHC isoforms via these different nuclear receptors. LÄS MER