Sökning: "Single-molecule"

Visar resultat 6 - 10 av 142 avhandlingar innehållade ordet Single-molecule.

  1. 6. Single-­molecule spectroscopy of π-­conjugated polymers

    Författare :Oleg Mirzov; Kemisk fysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; fluorescence lifetime; low temperature; spectral diffusion; blinking; MEH-PPV; Single-molecule spectroscopy; π-conjugated polymers; 2D polarization; Monte Carlo; energy transfer;

    Sammanfattning : When applied to condensed-matter samples of large organic molecules, optical spectroscopy faces the problem of inhomogeneous broadening caused by the diversity of environments and conformations that sample molecules are subjected to. This severely limits the information that can be extracted from optical spectra. LÄS MER

  3. 7. Biomolecular Analysis by Dual-Tag Microarrays and Single Molecule Amplification

    Författare :Olle Ericsson; Ulf Landegren; Mats Nilsson; Edwin Southern; Uppsala universitet; []
    Nyckelord :Molecular medicine; Microarray; proximity ligation; Padlock probe; Rolling circle amplification; Splicing; single molecule; Molekylärmedicin;

    Sammanfattning : Padlock probes and proximity ligation are two powerful molecular tools for detection of nucleic acids and proteins, respectively. Both methods result in the formation of DNA reporter molecules upon recognition of specific target molecules. LÄS MER

  4. 8. Single-molecule Detection in situ

    Författare :Chatarina Larsson; Mats Nilsson; Ulf Landegren; Sanjay Tyagi; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; Molekylär medicin; Molecular Medicine; molekylär medicin genetik och patologi ;

    Sammanfattning : The human body contains a variety of different cell types that share a common genome, but differ in how they use the information encoded therein. Variation in molecular content exists even at the level of individual cells, and to provide deeper insight into complex cellular processes methods that permit analysis of each cell on its own are needed. LÄS MER

  5. 9. Tracking single molecules in uncharted territory : A single-molecule method to study kinetics in live bacteria

    Författare :Javier Aguirre Rivera; Magnus Johansson; Dmitri N. Ermolenko; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; single-molecule; protein synthesis; fluorescence microscopy; antibiotics; aminoglycosides; macrolides; apramycin; gentamicin; paromomycin; S13; translation; bacteria; Molekylär biovetenskap; Molecular Life Sciences;

    Sammanfattning : The synthesis of proteins, also known as translation, is a fundamental process in every living organism. The steps in the translation of genetic information to functional proteins have been meticulously studied, mostly using in vitro techniques, yielding a detailed model of their mechanisms. LÄS MER

  7. 10. Development of Methods for Single-Molecule Studies of DNA in Nanofluidic Channels

    Författare :Lena Nyberg; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; fluorescence microscopy; YOYO-1; Nanofluidics; netropsin; competitive binding; DNA; single-molecule;

    Sammanfattning : .... LÄS MER