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Visar resultat 1 - 5 av 39 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Neuroactive steroids and rat CNS

   Författare :Vita Birzniece; Bo Söderpalm; Umeå universitet; []
   Nyckelord :Estradiol; progesterone; HRT; allopregnanolone; UC1011; serotonin receptor; GABAA receptor; mRNA; Morris water maze; silent second; tolerance; Clinical Neurophysiology; klinisk neurofysiologi;

   Sammanfattning : Several studies suggest profound effects on mood and cognition by neuroactive steroids. Estrogen alone or in combination with antidepressant drugs affecting the serotonin system has been used to treat mood disorders. On the other hand, progesterone is related to negative effects on mood and memory. LÄS MER

3. 2. Tolerance and antagonism to allopregnanolone effects in the rat CNS

   Författare :Sahruh Turkmen; Inga-Maj Johansson; Agneta Nordberg; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allopregnanolone; GABA-A receptor; UC1011; Spatial memory; Morris Water Maze; Tolerance; Silent second; mRNA; Obstetrics and gynaecology; Obstetrik och gynekologi;

   Sammanfattning : Many studies have suggested a relationship between sex steroids and negative mental and mood changes in women. Allopregnanolone, a potent endogenous ligand of the GABA-A receptor and a metabolite of progesterone, is one of the most accused neuroactive steroids. LÄS MER

4. 3. Neurotoxicity of β-lactam antibiotics : experimental kinetic and neurophysiological studies

   Författare :Silvia E. Schliamser; Ragnar Norrby; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; benzylpenicillin; blood-brain barrier; ß-lactam antibiotics; CSF; CNS; EEG; imipenem cilastatin; FCE 22101; meningitis; neurotoxicity of; silent-second; thiopental; transport system; uraemia;

   Sammanfattning : The neurotoxic potential of intravenous administered benzylpenicillin (BPC) was studied in rabbits with intact blood-CNS barriers and rabbits with experimental E. coli meningitis. At onset of epileptogenic EEG activity or seizures, serum, CSF and brain tissue were collected for assay of BPC. LÄS MER

5. 4. Prediction and Optimisation of Traffic Noise. A Study on Noise Barriers and Shielded Areas

   Författare :Pontus Thorsson; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; city canyon; absorption; city noise; insertion loss; traffic noise; soundscape; silent side; noise barrier; ground impedance;

   Sammanfattning : The main contribution of noise levels in cities is today road traffic. The strongest source for all road vehicles is most often the tyre-road contact. This source position close to the ground is fortunate with respect to secondary noise abatement measures, such as absorbing road surfaces or noise barriers. LÄS MER

7. 5. Techniques to Cancel Execution Early to Improve Processor Efficiency

   Författare :Mafijul Islam; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; processor design; energy-efficiency; narrow-width cache; instruction reuse; zero-value cache; resource-efficient; narrow-width load; complexity-effective; small value locality; register file cache; frequent value locality; trivial instruction; silent load; high-performance; zero load;

   Sammanfattning : The evolution of computer systems to continuously improve execution efficiency has traditionally embraced various approaches across microprocessor generations. Unfortunately, contemporary processors still suffer from several inefficiencies although they offer an unprecedented level of computing capabilities. LÄS MER