Sökning: "SiaT"
Hittade 3 avhandlingar innehållade ordet SiaT.
1. Structural and Functional Studies of Membrane Proteins For Future Development of Antimicrobial Drugs
Sammanfattning : Antibiotic resistance is a world-wide occurring problem which threatens human health. Without development of any new and effective antibiotics, the rapid growth of antibiotic-resistant bacterial infections could put society in a situation resembling the pre-antibiotic era when a simple lung infection could kill a human being. LÄS MER
2. Structural Insight into the Bacterial Sialic Acid Catabolic Pathway
Sammanfattning : A genetically diverse community of commensal and pathogenic bacteria thrive in the digestive system and urogenital tracts of animals. Many of these bacteria forage sialic acid from mucosal cell surfaces. LÄS MER
3. Design, synthesis and evaluation of bacterial sialic acid uptake inhibitors
Sammanfattning : Antibiotic resistance is a major threat for our society and finding novel antibacterial therapies is of greatimportance. In this thesis, we investigate bacterial sialic acid uptake inhibitors as a novel antibacterial approach.Bacteria do not biosynthesise sialic acid and therefore harvest it from the host. LÄS MER