Sökning: "Short-chain dehydrogenases reductases"
Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Short-chain dehydrogenases reductases.
1. Short-chain retinol dehydrogenases/reductases : Involvement in retinoid metabolism and expression in embryonic and adult mouse
Sammanfattning : Retinoids are needed in the embryo to ensure proper development and in the adult forvision, maintenance of epithelia and sperm production. Retinol is oxidised within the cell generating retinal and, irreversibly, retinoic acid. LÄS MER
Sammanfattning : X-ray crystallography and site-directed mutagenesis were used to better understand the structure/function relationships in the family of short-chain dehydrogenases/reductases (SDR). This group of enzymes constitutes a protein family with at least 60 members with highly diverse functions in pro- and eukaryotes. LÄS MER
3. Short-chain dehydrogenases/reductases : structure, function and motifs of hydroxysteroid dehydrogenases
Sammanfattning : Short-chain dehydrogenases/reductases (SDR) constitute a superfamily of proteins catalysing reactions of a wide range of substrates in all life forms. During the past years, a large number of new proteins belonging to this superfamily has been detected. They are important in e.g. LÄS MER
4. Substrate specificities and functional properties of human short-chain dehydrogenases / reductases
Sammanfattning : Short-chain dehydrogenases/reductases (SDRs) constitute a universal superfamily of functionally heterogeneous proteins and participate in the metabolism of steroids, prostaglandins, retinoids, aliphatic alcohols, and xenobiotics. So far, more than 3000 members including species variants and over 60 human SDR genes are deposited in databases. LÄS MER
5. Characterization of stress-inducible short-chain dehydrogenases/reductases (SDR) in plants : study of a novel small protein family from Pisum sativum (pea)
Sammanfattning : In pea (Pisum sativum), the short-chain alcohol dehydrogenase-like protein (SAD) gene family consists of at least three members (SAD-A, -B, and -C). The SAD genes are transiently expressed in plants after short exposures to ultraviolet-B radiation, which in turn leads to formation of SAD protein in leaf and stem tissue upon prolonged irradiation. LÄS MER