Sökning: "Shar"

Visar resultat 6 - 10 av 12 avhandlingar innehållade ordet Shar.

1. 6. Genetic Studies in Dogs Implicate Novel Genes Involved in Atopic Dermatitis and IgA Deficiency

   Författare :Katarina Tengvall; Kerstin Lindblad-Toh; Göran Andersson; Åke Hedhammar; Gerli Rosengren Pielberg; Ingrid Skelton Kockum; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GWAS; canine model; genetic association; immunogenetics; atopic dermatitis; IgA deficiency; Molekylär genetik; Molecular Genetics;

   Sammanfattning : This thesis presents genetic studies of atopic dermatitis (AD) and IgA deficiency in dogs.AD is a chronic inflammatory and pruritic skin disorder caused by allergic reactions against environmental allergens. Both genetic and environmental factors are involved in the development of Canine AD (CAD) and human AD. LÄS MER

3. 7. New policies at Nosokomio Neapolis : introducing small areas research and development in a Cretan primary/hospital care setting

   Författare :Marios Chatziarsenis; Calle Bengtsson; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : The present thesis gives an account of the scheduled transformation of a combined Hospital and Primary Health Care institution, Nosokomio Neapolis, in a semi-rural community on Crete to an integrated population health research and development (R&D) centre by relatively minor organisational updatings and focused scientific studies with academic and political support and supervision. This process has engaged the whole local team, and the thesis is concerned with some of its bearing "Ariadne threads". LÄS MER

4. 8. Bioinformatics mining for disease causing mutations : using the dog genome as a model for human disease

   Författare :Katarina Truvé; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Humans and dogs share many common diseases, and it has been shown that the identification of mutations that cause disease in dogs can help unravel the genetic basis for a similar disease in humans. Mapping of traits and disease in dogs is not a new idea, but the sequencing of the whole dog genome, the creation of a dense SNP maps followed by the development of SNP arrays for high throughput genotyping has led to new facilitated mapping procedures. LÄS MER

5. 9. Predicting mortality by comorbidity for patients with hip arthroplasty: Prospective observational register studies of a nationwide Swedish cohort : Prediktion av död baserat på samsjuklighet efter höftprotesoperation: Prospektiva registerstudier utifrån en nationell svensk kohort

   Författare :Erik Bülow; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hip arthroplasty; orthopaedics; shared decision model; epidemiology; prediction model; mortality; comorbidity; R-package; orthopaedics; osteoarthritis; femoral neck fracture; restricted mean survival time;

   Sammanfattning : INTRODUCTION: Patients with total hip arthroplasty (THA) due to osteoarthritis (OA) are usually healthy, some with a remaining lifetime of several decades after surgery. Patients with hip arthroplasty due to a femoral neck fracture (FNF) are often old and frail with 13 % mortality within 90 days of surgery. LÄS MER

7. 10. Who should have total hip replacement? Use of patient-reported outcome measures in identifying the indications for and assessment of total hip replacement

   Författare :Meridith E Greene; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Patient-reported outcome measures; Swedish Hip Arthroplasty Register; Harris Joint Registry; total hip replacement; health-related quality of life; EQ-5D; surgical recommendations;

   Sammanfattning : Background: Total hip replacement (THR) is a successful treatment for end-stage hip osteoarthritis (OA). Patients commonly seek this treatment to improve physical function, diminish pain, and ultimately to increase health-related quality of life (HRQoL). LÄS MER