Sökning: "Shane Peterson"

Hittade 1 avhandling innehållade orden Shane Peterson.

1. 1. Improved CoMFA Modeling by Optimization of Settings : Toward the Design of Inhibitors of the HCV NS3 Protease

   Författare :Shane Peterson; Anders Karlén; Anja Sandström; Ulf Norinder; Uppsala universitet; []
   Nyckelord :Pharmaceutical chemistry; CoMFA; 3D-QSAR; model validation; Docking; SAR; hepatitis C virus; HCV; NS3 protease inhibitor; Farmaceutisk kemi;

   Sammanfattning : The hepatitis C virus (HCV), with a global prevalence of roughly 2%, is among the most serious diseases today. Among the more promising HCV targets is the NS3 protease, for which several drug candidates have entered clinical trials. LÄS MER