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1. 1. Sex differences in immune response and sex hormone receptor expression in healthy individuals and during viral infection

   Författare :Peik M. A. Brundin; Anders F. Johansson; Ivan Nalvarte; Carl-Johan Treutiger; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; immune response; menstrual cycle; puumala virus; hantavirus; torque teno virus; sex hormones; sex hormone receptors; estrogen receptors; estrogen receptor beta2; sex differences; microbiome; virome; endocrinology; peripheral blood mononuclear cells; qPCR; Infectious Diseases; infektionssjukdomar; medicinsk virologi; Medical Virology; immunologi; Immunology; Medical Cell Biology; medicinsk cellbiologi; molekylärbiologi; Molecular Biology; Medicine; medicin; obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : There is sex-bias in morbidity and mortality from infectious diseases. Infections kill more men than women and several studies have pointed out differences in the immune system as a reason. The sex hormones estrogen, progesterone and testosterone all shape the effect of the immune response on multiple levels. LÄS MER

3. 2. Sex differences in children's play behavior : A biological construction of gender?

   Författare :Anna Servin; Uppsala universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Psychology; congenital adrenal hyperplasia; sex differences; children; play; expectations; wishes; hormones; biology; Psykologi; Psychology; Psykologi; Psychology; psykologi;

   Sammanfattning : The present thesis addressed the question of what causes sex differences in children's play behavior.In Study I, it was found that mothers have rather sex-stereotyped expectations for how their 1- and 3-year-old children will behave at the age of five, as regards sex-typed activities. LÄS MER

4. 3. Organisation of Asthma in Primary Care, Quality of Life and Sex-related Aspects in Asthma Outcomes

   Författare :Karin Lisspers; Gunnar Johansson; Kurt Svärdsudd; Kjell Larsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma; Primary Health Care; Cross-Sectional Studies; Quality of Health Care; Asthma clinic; Spirometer; Asthma management; Knowledge; Outcome Assessment; Control; Symptoms; Quality of Life; Sex; Menopause; Sex Hormones; Family medicine; Allmänmedicin;

   Sammanfattning : Objectives: To investigate the organisation of asthma care in primary care and evaluate outcomes for patients attending primary care centres with and without asthma clinics.Other objectives were to study the association between quality of life and asthma control in patients in primary care and to analyse sex differences regarding asthma outcomes related to menopausal status. LÄS MER

5. 4. Stroke, Sex and Vascular Receptor Changes in the Brain

   Författare :Hilda Ahnstedt; Lund Medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endothelin receptors; Cerebral ischemia; sex; estrogen; progesterone; sex differences; human cerebral arteries; endothelin-1; angiotensin II; middle cerebral artery occlusion; extra-cellular signal regulated kinase 1 and 2;

   Sammanfattning : Stroke is a severe cerebrovascular disease in which the neuronal tissue and vasculature of the brain undergo ischemia-evoked alterations. We have demonstrated an increased expression of cerebrovascular contractile receptors in the brain. This is hypothesized to mitigate cerebral blood flow and exacerbate tissue damage after stroke. LÄS MER

7. 5. Endogenous sex hormones and cardiometabolic risk factors – population-based studies within the Skaraborg Project

   Författare :Kristin Ottarsdottir; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sex hormones; sex hormone binding globulin; cardiometabolic risk factors; insulin resistance; post-menopause; cardiovascular diseases;

   Sammanfattning : Cardiovascular diseases are the major contributors to mortality in Sweden and globally. Men have a higher incidence of cardiovascular diseases compared to women, until women reach the menopause. Levels of sex hormones might explain these sex differences beyond known differences in risk factors. LÄS MER