Sökning: "Severe malaria"

Visar resultat 6 - 10 av 57 avhandlingar innehållade orden Severe malaria.

  1. 6. Antibody responses and Fc gamma receptor IIa polymorphism in relation to Plasmodium falciparum malaria

    Författare :Nnaemeka C. Iriemenam; Klavs Berzins; Marita Troye-Blomberg; Philippe Deloron; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; malaria; Plasmodium falciparum; blood-stage; antibodies; antigens; logistic models; risk factors; age factors; merozoites; IgG subclasses; Fc gamma RIIa; single nucleotide polymorphism; ethnicity; endemicity; disease susceptibility; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Immunity to asexual blood-stage of Plasmodium falciparum malaria is believed to be associated with protective antibodies of certain immunoglobulin classes and subclasses. This thesis addressed the importance of antibodies in relation to malaria infection and their effective interactions with Fc gamma receptor IIa (FcyRIIa) polymorphisms. LÄS MER

  3. 7. Managing malaria in under-fives : prompt access, adherence to treatment and referral in rural Tanzania

    Författare :Daudi Simba; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Malaria;

    Sammanfattning : Background: Nearly a million people die of malaria each year, the majority are children in rural African settings. These deaths could be reduced if children had prompt access to artemisinin-based combination therapy (ACTs), demonstrated adherence to treatment and to referral advice for severe malaria. LÄS MER

  4. 8. Malaria in travellers and migrants

    Författare :Andreas Wångdahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malaria is a potentially fatal disease that caused approximately 241 million cases and 627 000 deaths in 2020, most in children in Sub-Saharan Africa. In non-endemic countries, malaria is imported by travellers and migrants and timely management and treatment is crucial. LÄS MER

  5. 9. Immune Regulation During Malaria Infection

    Författare :Helena Helmby; Edvard Pearce; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; immunologi; Immunology;

    Sammanfattning : Malaria is the largest parasitic disease in the world and is caused by the protozoon Plasmodium. The most severe form in humans is caused by Plasmodium falciparum. Immunity to malaria involves both cell-mediated and humoral responses and develops slowly over a period of ten to fifteen years, requiring repeated infections. LÄS MER

  7. 10. Malaria during pregnancy and childhood : A focus on soluble mediators and neutrophils

    Författare :Stéphanie Boström; Marita Troye-Blomberg; Maria Yazdanbakhsh; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plasmodium falciparum; pregnancy; childhood; neutrophils; biomarkers; cytokines; chemokines; antibodies; Fulani; Dogon; immunologi; Immunology;

    Sammanfattning : In areas where malaria is endemic, pregnant women and children bear the main burden of severe and life-threatening malarial disease. The aim of this work was to study the impact of Plasmodium falciparum infection on inflammatory responses in pregnant women and children residing in African countries. LÄS MER