Sökning: "SelS"

Hittade 4 avhandlingar innehållade ordet SelS.

  1. 1. Insulin signaling and glucose transport in insulin resistant human skeletal muscle

    Författare :Håkan K R Karlsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Skeletal muscle; insulin resistance; type 2 diabetes; glucose transport; insulin signaling; first-degree relatives; AS160; SelS; rosiglitazone treatment;

    Sammanfattning : Insulin resistance in skeletal muscle is a hallmark feature of Type 2 diabetes mellitus. The overall aim of this thesis was to investigate downstream intermediates in the insulin signaling pathway in an attempt to characterize the molecular mechanism of skeletal muscle insulin resistance in Type 2 diabetes. LÄS MER

  3. 2. Tenomodulin, serum amyloid A and the serum amyloid A receptor selenoprotein S – implications for metabolic disease

    Författare :Maja Olsson; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : Obesity and obesity-related metabolic diseases are associated with a low-grade inflammation, including slightly increased serum levels of the acute phase protein serum amyloid A (A-SAA). A-SAA is one amongst several adipose tissue (AT) produced proteins suggested to influence development of metabolic diseases. LÄS MER

  4. 3. Endosonography and pretreatment tumor profiling - from sampling, staining, to sequencing

    Författare :Per Hedenström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endosonography; fine-needle biopsy; pancreatic neoplasms; gastrointestinal stromal tumors; KIT; PDGFRA; Ki-67; imatinib; neoadjuvant therapy;

    Sammanfattning : Background and aims: Endosonography-guided fine needle aspiration (EUS-FNA) is imperfect in diagnosing solid pancreatic lesions (SPL) and subepithelial lesions (SEL) including gastrointestinal stromal tumors (GIST). In GISTs, imatinib therapy is effective only in variants of oncogenes KIT and PDGFRA. LÄS MER

  5. 4. Middle ear structure in relation to function : the rat in middle ear research

    Författare :Nils Albiin; Umeå universitet; []
    Nyckelord :rats; Eustachian tube; ear; middle; tympanic membrane; palatal muscles; mucous membrane; blood vessels; mast cells; otitis media; microscopy; electron;

    Sammanfattning : The present study was undertaken to evaluate the rat as a model for middle ear re­search. The rat was chosen primarily because the gross structure of its middle ear shows several similarities to that of man. LÄS MER