Sökning: "Secondary brain injury"

Visar resultat 16 - 20 av 59 avhandlingar innehållade orden Secondary brain injury.

1. 16. Cerebral Hemodynamics through Intracrnial Pressure

   Författare :Sima Shahsavari; Chalmers tekniska högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Intracranial dynamics; Baroreceptor reflex; Secondary brain injury; Traumatic brain injury; Collapsible tubes; Intracranial pressure; Cushing reflex; Pulse wave propagation; Cerebral autoregulation; Cerebral compliance; Mathematical modelling;

   Sammanfattning : Traumatic Brain Injury (TBI) continues to be a major problem worldwide. Today, intensive care of patients with TBI is mainly focused on preventing and treating secondary brain injuries. High pressure inside the intracranial cavity has been found to be an important feature of disturbed cerebral dynamics and secondary injuries. LÄS MER

3. 17. Aspects on Mechanisms, Treatment and Outcome in Severe Traumatic Brain Injury

   Författare :Teodor Svedung Wettervik; Anders Lewén; Per Enblad; Elham Rostami; Lars-Owe Koskinen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoregulation; clinical outcome; energy metabolism; multimodality monitoring; neurointensive-care; traumatic brain injury; Neurokirurgi; Neurosurgery;

   Sammanfattning : Traumatic brain injury (TBI) is a leading cause for mortality and morbidity worldwide. The primary injury has great impact on patient outcome and cannot be cured, but attentive neurointensive care (NIC) may reduce detrimental secondary brain injuries and is the focus of this thesis. LÄS MER

4. 18. Perinatal brain injury - markers and mediators. Non-protein-bound iron and pro-inflammatory cytokines in newborn infants and neonatal pigs

   Författare :Karin Sävman; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asphyxia; hypoxia; posthemorrhagic ventricular dilatation; preterm; newborn; perinatal; brain; cerebrospinal fluid; cytokines; IL-1ß; IL-6; IL-8; TNF-a; non-protein-bound-iron;

   Sammanfattning : Two groups of newborn infants have an increased risk for perinatal brain injury; preterm infants and term infants subjected to birth asphyxia. Experimental studies indicate that hypoxic-ischemic insults in the perinatal period initiate a secondary neurotoxic cascade including formation of toxic reactive oxygen species as well as an inflammatory response with elevated levels of potentially neurotoxic cytokines. LÄS MER

5. 19. Cellular and molecular mechanisms of ischemic brain damage in hyperglycemic rats

   Författare :Hiroyuki Uchino; Lund Wallenberg Neurocentrum; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Reperfusion injury; Mitochondria; Permeability transition; Cyclosporin A; Neurotrophins; Seizures; Brain damage; Acidosis; Hypercapnia; Ischemia; Hyperglycemia; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

   Sammanfattning : The present study is centered on mechanisms of ischemic brain damage in hyperglycemic animals, and in those in which exaggerated intraischemic acidosis was induced by superimposed hypercapnia in normoglycemic animals. The initial experiments were focussed on the pathophysiology of postischemic seizures. LÄS MER

7. 20. Oxidative stress in experimental traumatic brain injury

   Författare :Mattias Günther; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Traumatic brain injury (TBI) is a leading cause of death and disability among the young population in the industrialized world. The injury consists of immediate damage to the brain tissue, followed by a secondary response involving inflammation and oxidative stress. LÄS MER