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Visar resultat 1 - 5 av 59 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Intracranial Pressure in Traumatic Brain Injury

   Författare :Sima Shahsavari; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Brain Swelling; Cerebral Autoregulation; Secondary Brain Injury; Traumatic Brain Injury; Cerebral Compliance; Intracranial Dynamics; Intracranial Pressure;

   Sammanfattning : Traumatic Brain Injury (TBI) continues to be a major problem worldwide. Today, intensive care of patients with TBI is mainely focused on preventing and treating secondary brain injuries. High pressure inside the intracranial cavity (ICP) has been found to be an important feature of disturbed cerebral dynamics and secondary injuries. LÄS MER

3. 2. Brain Tissue Oxygenation in Traumatic Brain Injury : Experimental and Clinical Studies

   Författare :Karlis Purins; Anders Lewén; Per Enblad; Oliver Sakowitz; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain tissue oxygenation; Cerebral metabolism; Traumatic brain injury; Cerebral ischemia; Threshold levels; Neurovent-PTO; Microdialysis; Neurosurgery; Neurokirurgi;

   Sammanfattning : Traumatic brain injury (TBI) is a major cause of death and disability. TBI is frequently followed by cerebral ischemia which is a great contributor to secondary brain damage. The main causes of cerebral ischemia are pathophysiological changes in cerebral blood flow and metabolism. LÄS MER

4. 3. Traumatic brain injury in elderly patients

   Författare :Samuel Lenell; Per Enblad; Anders Lewén; Alfonso Lagares; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traumatic brain injury; Elderly; Outcome; Standardized neurosurgical intensive care; Quality register; Prognostic factors; Secondary insults; Neurointensive care monitoring; Pressure reactivity index; Optimal cerebral perfusion pressure; Cerebral autoregulation; Neurokirurgi; Neurosurgery;

   Sammanfattning : The increase of elderly traumatic brain injury (TBI) patients constitutes a considerable challenge. The aim was therefore to specifically study elderly TBI patients with respect to patient characteristics, neurointensive care (NIC) and outcome, and to identify age specific features, which may be important for selection of patients and optimization of NIC in the elderly. LÄS MER

5. 4. Delayed Cell Death after Traumatic Brain Injury : Role of Reactive Oxygen Species

   Författare :Fredrik Clausen; Lars Hillered; Tiit Mathiesen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Traumatic Brain Injury; Reactive oxygen species; Fluid percussion injury; Controlled cortical impact; weight drop injury; Extracellular-signal regulated kinase; apoptosis; free radical scavenging; morphology; functional outcome; Neurovetenskap; Neurology; Neurologi;

   Sammanfattning : Traumatic brain injury (TBI) is a leading cause of death and disability TBI survivors often suffer from severe disturbances of cognition, memory and emotions. Improving the treatment is of great importance, but as of yet no specific neuroprotective treatment has been found. LÄS MER

7. 5. Oligodendrocyte pathology following Traumatic Brain Injury : Experimental and clinical studies

   Författare :Johanna Flygt; Niklas Marklund; Fredrik Piehl; Uppsala universitet; []
   Nyckelord :Traumatic brain injury; oligodendrocytes; oligodendrocyte progenitor cells; interleukin 1-β; central fluid percussion injury; Neurokirurgi; Neurosurgery; Neurokirurgi; Neurosurgery;

   Sammanfattning : Traumatic brain injury (TBI) caused by traffic and fall accidents, sports-related injuries and violence commonly results in life-changing disabilities. Cognitive impairments following TBI may be due to disruption of axons, stretched by the acceleration/deceleration forces of the initial impact, and their surrounding myelin in neuronal networks. LÄS MER