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1. 1. Mechanosensing in the vascular wall - the role of cellular microdomains in vascular remodeling

   Författare :Sebastian Albinsson; Kärlfysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; tissue culture; Histologi; cytokemi; histokemi; vävnadskultur; cytochemistry; histochemistry; wall stress; shear stress; hypertension; Histology; differentiation; growth; caveolin; smooth muscle; actin; Fysiologi; Cardiovascular system; Kardiovaskulära systemet;

   Sammanfattning : The vascular wall has a remarkable capacity to adapt to mechanical forces exerted by the intraluminal blood pressure and flow. This includes rapid change in contractile tone as well as chronic alteration of vessel structure if the stimulus persists. Stretch of the intact blood vessel wall promotes growth and contractile differentiation. LÄS MER