Sökning: "Scleroderma"

Visar resultat 1 - 5 av 8 avhandlingar innehållade ordet Scleroderma.

  1. 1. Hand function, Everyday Occupations and Wellbeing in Individuals with Systemic Sclerosis

    Författare :Gunnel Sandqvist; Hållbar vardag och hälsa i ett livsperspektiv; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; arbetsmiljömedicin; Yrkesmedicin; industrial medicine; Occupational health; occupational therapy interventions; wellbeing; everyday occupations; Systemic sclerosis; hand function;

    Sammanfattning : Systemic sclerosis (scleroderma) is a connective tissue disease which, in various ways, influences an individual’s ability to participate in everyday occupations. The general objective of this work was to elucidate the consequences of scleroderma with respect to hand function, everyday occupations and wellbeing, in order to provide a knowledge base suitable for occupational therapy interventions. LÄS MER

  3. 2. Analysis of phenotype reversibility in Hutchinson-Gilford progeria syndrome in mice

    Författare :Charlotte Strandgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Aging affects all people and is a complex process involving both genetic and environmental factors in a way that is not yet completely understood. Studies of premature aging syndromes might be helpful to acquire further clues to understand the molecular mechanisms explaining how aging occurs. LÄS MER

  4. 3. Novel Analysis Toolkit for Capillaroscopic Images: Development and Clinical Evaluation

    Författare :Abdolamir Karbalaie; Björn-Erik Erlandsson; Olof Lindahl; KTH; []
    Nyckelord :Nailfold videocapillaroscopy; Image enhancement; Inter and intra-observer reliability; Tillämpad medicinsk teknik; Applied Medical Technology;

    Sammanfattning : Nailfold capillaroscopy (NC) is an invasive imaging technique that is used to assess the blood capillary network in the nailfold area. NC is routinely used for patients with microcirculation problems, such as systemic sclerosis and other connective tissue diseases. NC is repeatable and appears to be simple and harmless. LÄS MER

  5. 4. Mercury-induced autoimmunity : Genetics and immunoregulation

    Författare :Monika Hansson; Manuchehr Abedi-Valugerdi; Marita Troye-Blomberg; Lucette Pelletier; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mercury; autoimmunity; collagen-induced arthritis; Th1 Th2; silver; tight-skin 1 mice; Immunology; Immunologi;

    Sammanfattning : The existence of immune self-tolerance allows the immune system to mount responses against infectious agents, but not against self-molecular constitutes. Although self-tolerance is a robust phenomenon, in some individuals as well as in experimental models, the self-tolerance breaks down and as a result, a self-destructive autoimmune disease emerges. LÄS MER

  7. 5. Primary biliary cirrhosis : an epidemiological and clinical study based on patients from northern Sweden

    Författare :Per Uddenfeldt; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Primary biliary cirrhosis; incidence; prevalence; disease course; Kveim test; sarcoidosis; rheumatic disorders; lung function; diffusing capacity; Sjögren syndrome; von Willebrand factor;

    Sammanfattning : Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease, which primarily affects middle-aged women. The liver histology is characterized by inflammation and destruction of the intrahepatic bile ducts as well as a high frequency of granuloma. LÄS MER