Sökning: "Scan"

Visar resultat 11 - 15 av 369 avhandlingar innehållade ordet Scan.

1. 11. Genetic Mapping of Susceptibility Genes for Systemic Lupus Erythematosus

   Författare :Bo Johanneson; Jean Pierre Hugot; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Association analysis; Candidate gene; Complex disease; Genome scan; Linkage analysis; Mapping; Susceptibility genes; Systemic lupus erythematosus; Genetik; Genetics; Genetik; medicinsk genetik; Medical Genetics;

   Sammanfattning : Systemic lupus erythematosus (SLE) is a complex autoimmune disease with unknown etiology. The aim of this thesis was to identify susceptibility regions through genetic mapping, using model-based linkage analysis on nuclear and extended SLE multicase families. LÄS MER

3. 12. Assessment and Comparison of Physical Fault Injection Techniques

   Författare :Peter Folkesson; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; fault tolerance; concurrent error detection; dependability; coverage; fault injection; experimental validation; boundary scan;

   Sammanfattning : This thesis deals with the problem of validating and estimating the effectiveness of error handling mechanisms in computer systems. The main contribution is an assessment of the effectiveness and usefulness of several physical fault injection techniques. LÄS MER

4. 13. Genetic Analysis of Quantitative Traits Using Domestic Animals : A Candidate Gene and Genome Scanning Approach

   Författare :Hee-Bok Park; Leif Andersson; Stefan Marklund; Robert Fredricksson; Holger Luthman; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Domestication; horse; pig; chicken; quantitative traits; candidate gene; genome scan; PRKAG3; MC4R; selection experiment; growth; correlated response; metabolic disorders; Quantitative Trait Loci; linkage; single nucleotide polymorphisms; Genetik; Clinical genetics; Klinisk genetik;

   Sammanfattning : Domestication has led to genetic changes that affect quantitative traits in farm animals. Both candidate gene analysis using association tests and genome scans based on linkage analysis have been performed to understand the molecular basis underlying quantitative genetic variation in horses, pigs and chickens. LÄS MER

5. 14. Long-term follow-up of adult women with urinary tract infection in childhood

   Författare :Carin Gebäck; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ambulatory blood pressure; blood pressure; chronic kidney disease; DMSA scan; glomerular filtration rate; hypertension; pregnancy; renal damage; renal function; urinary tract infection; vesicoureteral reflux;

   Sammanfattning : Acute pyelonephritis is common in young children and can lead to permanent renal damage. Renal damage increases the risk of complications such as hypertension and decreased renal function later in life. For women with renal damage there is also an increased risk of pregnancy complications. LÄS MER

7. 15. On the genetics of hereditary breast/ovarian cancer. BRCA1, BRCA2 and beyond

   Författare :Annika Bergman; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; BRCA1; BRCA2; breast cancer; hereditary cancer; founder mutation; mutation analysis; linkage analysis; genome scan; BRCAX;

   Sammanfattning : Breast cancer is the most common malignancy in women. Most of the breast cancers are sporadic with no apparent inheritance factor but about 5-10% is believed to be caused by an inherited predisposition. Aims: This thesis aimed at defining the BRCA1/2 mutation spectrum of the west Swedish population and specifically to characterize the BRCA1c. LÄS MER