Sökning: "Sarcomas"

Visar resultat 1 - 5 av 42 avhandlingar innehållade ordet Sarcomas.

  1. 1. Chest wall sarcomas

    Författare :Björn Widhe; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Aim: To evaluate initial symptoms and clinical features, diagnosis and delay in osteosarcoma (OS), Ewing sarcoma (EWS) and chest wall chondrosarcoma (CS). To assess treatment and identify prognostic factors in chest wall CS. LÄS MER

  3. 2. Massively Parallel Sequencing of Gene Fusion-Associated Sarcomas

    Författare :Jakob Hofvander; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sarcomas; Gene fusion; tumor evolution; clonal heterogeneity; RNA-seq; WES; SNP-array;

    Sammanfattning : .... LÄS MER

  4. 3. Growth regulation in sarcomas : studies in vivo and in cell culture

    Författare :Avni Abdiu; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Sarcomas are malignant tumors of mesenchymal origin, and can arise in soft-tissue and in bones. It has been suggested that the abnormal growth regulation in sarcoma cells may be due to an autocrine mechanism, in which the cells are stimulated by an endogenous production of growth factors. LÄS MER

  5. 4. Pathogenetic Mechanisms in Soft Tissue Tumors

    Författare :Elsa Arbajian; Avdelningen för klinisk genetik; []
    Nyckelord :Soft tissue tumors; Sarcomas; Gene fusions; SNP array; Next generation sequencing; Haploidization; Point mutations;

    Sammanfattning : Soft tissue tumors (STT) constitute a heterogeneous group of tumors that arise in tissues of mesenchymal origin. They are currently classified according to morphology and resemblance to normal tissue into over 100 subtypes. LÄS MER

  7. 5. Genetic and molecular mechanisms of sarcomas

    Författare :Yi Chen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Sarcomas are heterogeneous malignant mesenchymal tumors with diverse biological features and unique clinical characteristics, the genetic alterations of sarcomas are highly variable. With the development of sequencing technologies, efficient and practical approaches to detect gene expressions and gene variants contribute to the prediction of patient prognosis and the choice of treatment modalities. LÄS MER