Sökning: "Sara Kinhult"

Hittade 1 avhandling innehållade orden Sara Kinhult.

  1. 1. Endothelial and cardiac effects of 5-fluorouracil. An experimental and clinical study

    Författare :Sara Kinhult; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancerology; oncology; Cytology; endothelin; onkologi; Cytologi; cancer; von Willebrand factor; thrombomodulin; lipoperoxidation; probucol; low-molecular weight heparin; scanning electron microscopy; 5-fluorouracil; endothelium;

    Sammanfattning : The cytostatic drug 5-fluorouracil (5-FU) has been shown to affect both morphology and function of vascular endothelium. These effects could be part of the pathophysiology for 5-FU induced cardiotoxicity. The present thesis explores the mechanisms of this endothelial toxicity. LÄS MER