Sökning: "Sara K. Olofsson"

Hittade 1 avhandling innehållade orden Sara K. Olofsson.

1. 1. Relation Between Drug Exposure and Selection of Antibiotic Resistant Bacteria

   Författare :Sara K. Olofsson; Otto Cars; Dan I. Andersson; Diarmaid Hughes; George G. Zhanel; Uppsala universitet; []
   Nyckelord :Microbiology; Pharmacokinetics; Pharmacodynamics; Antibiotic resistance; Selection; Transmission; Mathematical model; Escherichia coli; Mikrobiologi;

   Sammanfattning : The worldwide increase in antibiotic resistance is a concern for public health. When the appropriate antibiotic dosage is determined, the priorities are efficacy and toxicity. The aim of this thesis was to gain knowledge about the most efficient dosing regimens in order to minimize the emergence and selection of antibiotic-resistant mutants. LÄS MER