Sökning: "Sara I Wilson"

Hittade 4 avhandlingar innehållade orden Sara I Wilson.

  1. 1. Role of extracellular ATP in immune mechanisms against infections

    Författare :Lalitha Tadala; Andrea Puhar; Sara I Wilson; Bernt Eric Uhlin; Mikael Sellin; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Extracellular ATP; invasive bacteria; Shigella; Listeria; plasma membrane ruffle; PIEZO1; infection; immune response; Hanta virus; molekylär cellbiologi; molecular cell biology;

    Sammanfattning : Inflammation is driven either by infection with pathogens or sterile stimuli, such as tissue damage or autoimmune diseases. Upon tissue damage, ATP is released passively from the dead or compromised cells. During stress, ATP can be secreted from the cells. Extracellular ATP (eATP) acts as an endogenous danger signal. LÄS MER

  2. 2. Molecular mechanisms of nerve-tumor interactions : the intersection of cancer and neurodevelopment

    Författare :Luz Maria Gonzalez-Castrillon; Sara I Wilson; Daniel Öhlund; Nisha D’Silva; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Perineural invasion; cancer; PDAC; axonogenesis; neurodevelopment; spinal cord; axon guidance; bioinformatics.; biomedical laboratory science; biomedicinsk laboratorievetenskap;

    Sammanfattning : A wide range of cancers throughout the body are characterized by high nerve density and invasion of cancer cells within the nerves, a process called perineural invasion (PNI). Work in the field has shown that blocking nerves in organs with tumors leads to improved disease outcomes suggesting that finding ways to block tumor nerves could lead to new treatment approaches. LÄS MER

  3. 3. A molecular exploration of sensory responses in c. elegans

    Författare :Longjun Pu; Changchun Chen; Simon Tuck; Sara I Wilson; Zhiyong Shao; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; C. elegans; sensation; CRISPR Cas9; G protein-coupled receptors; neuropeptides; acute hypoxia; pathogen; chemosensation; hydrogen sulfide; HIF-1; iron;

    Sammanfattning : Sensation provides a pivotal ability, allowing animals to survive in complex environments. The cues sensed by animals are represented by external stimuli and internal signals. However, the mechanisms mediating sensations in molecular and cellular level are still not well-studied. In this thesis, by using free-living nematodes C. LÄS MER

  4. 4. The Archive Art Phenomenon : History and Critique at the Turn of the Twenty-First Century

    Författare :Sara Callahan; Anna Dahlgren; Dan Karlholm; Anna Orrghen; Stockholms universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; archival art; archival turn; archive art; contemporary art; critical paradigm; the Institutional Theory of Art; Institutional Critique; parafiction; postcritique; presentism; travelling concepts; The Atlas Group; Arthur Danto; Jacques Derrida; Michel Foucault; Joachim Koester; Zoe Leonard; Michael Maranda; Walid Raad; Raqs Media Collective; Ed Ruscha; Fred Wilson; konstvetenskap; Art History;

    Sammanfattning : This dissertation investigates the relationship between art and archive at the turn of the twenty-first century. The object of study is the phenomenon of archive art, understood as a combination of theories of the archive, artworks, and different kinds of texts (catalogues, scholarly articles, critical essays, etc. LÄS MER