Sökning: "Sara Bergström"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Sara Bergström.

  1. 1. Development of Integrated Micro-Analytical Systems

    Författare :Sara Bergström; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  3. 2. Integrated Micro-Analytical Tools for Life Science

    Författare :Sara Bergström; Karin Markides; Marit Andersson; Marja-Liisa Reikkola; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Microdialysis; Multidimensional separation; Liquid chromatography LC ; Capillary electrophoresis CE ; Electrospray ionisation ESI ; Mass spectrometry MS ; Microchip device; Free drug concentration; Screening of microdialysates; Pattern recognition; Analytisk kemi; Analytical chemistry; Analytisk kemi;

    Sammanfattning : Advances in life science require knowledge of active molecules in complex biological systems. These molecules are often only present for a certain time and at limited concentrations. LÄS MER

  4. 3. Ex‘PLA’ining the progression of pathological proteins in Alzheimer’s and Parkinson’s diseases : see(d)ing is believing

    Författare :Anish Behere; Joakim Bergström; Sara Ekmark-Lewén; Martin Ingelsson; Stina Syvänen; Hilal Lashuel; Uppsala universitet; []
    Nyckelord :Alpha synuclein; Tau; Proteoforms; Phosphorylation; Oligomers; Proximity Ligation Assay; sensitive detection of pathology; Alzheimer s disease; Parkinson s disease; pS129; pS202 pT205; pT231; PFFs;

    Sammanfattning : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the two most common forms of neurodegenerative disorders affecting approximately 50 million people worldwide. The underlying neuropathological processes leading to AD and PD share many similarities, i.e. aberrant protein aggregation of tau and alpha-synuclein (αSyn) in the brain. LÄS MER

  5. 4. Proteomic Analysis of Urinary Bladder Cancer : Aiming for Novel Biomarkers

    Författare :Mårten Lindén; Per-Uno Malmström; Ulrika Segersten; Sara Bergström Lind; Lars Egevad; Uppsala universitet; []
    Nyckelord :urine; APOE; FGB; GAL1; LRG1; POLR1E; SERPINA1; STMN1; TOP2A; biomarker; diagnostic biomarker; prognostic biomarker; predictive biomarker; mass spectrometry; western blot; dot blot; immunohistochemistry; IHC; tissue microarray; TMA; urothelium; antibody; antibody-based; urinblåsecancer; biomarkör; diagnos; prognos; urin; proteomik; masspektrometri; immunohistokemi; antikroppar; Molecular Biology; Molekylärbiologi; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Urinary bladder cancer is a heterogeneous disease appearing in different forms, e.g. non-muscle invasive and muscle invasive. For all variants, the expression of proteins is interesting to analyze for diagnostic, predictive, prognostic and drug targeting purposes, since it reflects the altered gene expression causing the cancer. LÄS MER

  7. 5. Characterization of Molecular Adsorption Using Liquid Chromatography and Mass Spectrometry

    Författare :Torgny Undin; Andreas Dahlin; Sara Bergström Lind; Jonas Bergquist; Elsa Lundanes; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

    Sammanfattning : Molecular adsorption is a key feature in several disciplines of chemistry, covering as diverse fields as chromatographic separation to biomaterial development. This thesis aims at developing methods and techniques for the characterization of molecular adsorption at the liquid-solid interface. LÄS MER