Sökning: "Sandra Irenaeus"
Hittade 1 avhandling innehållade orden Sandra Irenaeus.
1. Intratumoral CD40 stimulating therapy in patients with advanced cancer
Sammanfattning : CD40-CD40L interaction activates DCs to become highly efficient APCs and skews the adaptive immune response towards a Th I phenotype driving cytotoxic T cells, M1 macrophages and natural killer cells. Furthermore, engagement of CD40L to CD40 positive cancer cells can have direct anti-proliferative effects, induce apoptosis and increase expression of MHC and other co-stimulatory molecules, thereby enhancing cancer cell recognition. LÄS MER
Resultatsidor:
1