Sökning: "Sanaz"

Hittade 3 avhandlingar innehållade ordet Sanaz.

  1. 1. Search for markers and molecular mechanisms of aggressive endometrial cancer : profiling of aggressive vs non-aggressive endometrial cancers

    Författare :Sanaz Attarha; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Endometrial cancer is the seventh frequent type of cancer among women. Identification of new prognostic markers is important to optimize treatment and follow-up of all EC patients. Understanding the molecular mechanisms of carcinogenesis may pave through discovery of further EC molecular markers. LÄS MER

  3. 2. New perspectives on pathology in Huntington's disease - characterization of hypothalamic changes

    Författare :Sanaz Gabery; Translationell neuroendokrinologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Huntington’s disease; huntingtin; hypothalamus; oxytocin; vasopressin; orexin; CART; neuroendocrinology; MRI; 3 Tesla; volymetric analysis;

    Sammanfattning : Huntington’s disease (HD) is a neurodegenerative disorder caused by an expansion of the CAG repeat in the huntingtin gene. Non-motor symptoms and signs such as psychiatric disturbances and metabolic dysfunction are also part of the disease manifestation. These symptoms often precede the motor symptoms by decades. LÄS MER

  4. 3. Dynamic Resampling for Preference-based Evolutionary Multi-objective Optimization of Stochastic Systems : Improving the efficiency of time-constrained optimization

    Författare :Florian Siegmund; Kalyanmoy Deb; Amos H.C. Ng; Sanaz Mostaghim; Högskolan i Skövde; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Evolutionary multi-objective optimization; simulation-based optimization; guided search; preference-based optimization; reference point; decision support; noise; stochastic systems; dynamic resampling; budget allocation; sequential sampling; hybrid; ranking and selection; Natural sciences; Naturvetenskap; Technology; Teknik; Production and Automation Engineering; Produktion och automatiseringsteknik;

    Sammanfattning : In preference-based Evolutionary Multi-objective Optimization (EMO), the decision maker is looking for a diverse, but locally focused non-dominated front in a preferred area of the objective space, as close as possible to the true Pareto-front. Since solutions found outside the area of interest are considered less important or even irrelevant, the optimization can focus its efforts on the preferred area and find the solutions that the decision maker is looking for more quickly, i. LÄS MER