Sökning: "Samuel Svensson"

Visar resultat 6 - 10 av 10 avhandlingar innehållade orden Samuel Svensson.

  1. 6. Characterization of Diagnostic Tools and Potential Treatments for Alzheimer’s Disease : PET ligands and BACE1 inhibitors

    Författare :Fredrik Jeppsson; Anna-Lena Ström; Kerstin Iverfeldt; Samuel Svensson; Martin Hallbeck; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Alzheimer’s disease; Diagnostics; Treatment; PET ligand; BACE1; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Alzheimer’s disease (AD) is a very complex disorder and the most common form of dementia. The two pathological hallmarks of AD are extracellular amyloid-β (Aβ) plaques in cerebral cortex, and intraneuronal neurofibrillary tangles. LÄS MER

  2. 7. Signaling for color change in melanophores : and a biosensor application

    Författare :Annika M. Karlsson; Samuel Svensson; Margareta Wallin; Linköpings universitet; []
    Nyckelord :color change; melanophores; tyrosine; phosphorylations; melatonin; nitric oxide; MEDICINE; MEDICIN;

    Sammanfattning : Melanophores are dark brown pigment cells located in the skin of fish, amphibia, reptiles, and many invertebrates. The color of the animal can change via rearrangement of pigment granules, melanosomes, in the cells. The dark melanophores can either hide colorful cells so that the animal appears dark, or let through colors from underneath. LÄS MER

  3. 8. Lysophosphatidic acid : Physiological effects and structure-activity relationships

    Författare :Ulrika K. Nilsson; Samuel Svensson; Karin E. Bornfeldt; Linköpings universitet; []
    Nyckelord :Lysophospholipids pharmacology; physiology; structure-activity relationship; muscle; smooth; drug effects; myometrium; norepinephrine; epinephrine; signal transduction; MEDICINE; MEDICIN;

    Sammanfattning : Lipids havepreviously been considered primarily as building blocks of the cell membrane, but are now also recognized as important cell signaling molecules. Lysophosphatidic acid (LPA) is a glycerophospholipid consisting of a phosphate head group, a linker region, and a lipophilic tail. LÄS MER

  4. 9. Evolutionary and Pharmacological Studies of NPY and QRFP Receptors

    Författare :Bo Xu; Dan Larhammar; Samuel Svensson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Neuropeptide Y; genome duplication; Evolution; vertebrate; Pharmacology; Modelling; Kinetics; Bioinformatik; Bioinformatics; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik; Biologi med inriktning mot evolutionär funktionsgenomik; Biology with specialization in Evolutionary Functional Genomics; Farmaceutisk farmakologi; Pharmaceutical Pharmacology;

    Sammanfattning : The neuropeptide Y (NPY) system consists of 3-4 peptides and 4-7 receptors in vertebrates. It has powerful effects on appetite regulation and is involved in many other biological processes including blood pressure regulation, bone formation and anxiety. LÄS MER

  5. 10. The Sublime : Precursors and British Eighteenth-Century Conceptions

    Författare :Karl Axelsson; Lars-Olof Åhlberg; Tommie Zaine; Christina Svensson; Uppsala universitet; []
    Nyckelord :Aesthetics; the sublime; Longinus; Peri Hupsous; British eighteenth century; Samuel H. Monk; criticism of intellectual literature; Thomas Hobbes; imagination; Estetik;

    Sammanfattning : This dissertation studies the attraction of the sublime in British criticism during the eighteenth century, with particular emphasis on the arguments that served as precursors to the interest in the experience of the sublime. The first part explores Samuel H. LÄS MER