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Visar resultat 1 - 5 av 12 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Design, Synthesis, and Evaluation of Functionalized Chroman-4-one and Chromone Derivatives. Somatostatin receptor agonists and Sirt2 inhibitors

   Författare :Maria Fridén-Saxin; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chroman-4-ones; Chromones; Inhibitors; Molecular Modeling; Peptidomimetic; Samarium; Sirtuin; Sirt2; Somatostatin; Structure-Activity Relationships; Tubulin; β-Turn;

   Sammanfattning : Peptides are involved in many physiological processes such as regulation of blood-pressure, food intake, pain transmission and blood-glucose levels. They consist of amino acids that are connected through amide bonds which make peptides hydrophilic and conformationally flexible. LÄS MER

3. 2. A study of mixed valence in Sm by XPS and LEED when it is deposited onto Pd(001)

   Författare :Dan K. Kristensson; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; rare earth metals; XPS; x-ray photoemission; ESCA; intermediate valence; Low energy electron diffraction; mixed valence; Samarium; LEED;

   Sammanfattning : .... LÄS MER

4. 3. Samarium(II)-mediated Reactions in Organic Synthesis - Method Development and Mechanistic Investigation

   Författare :Tobias Ankner; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Samarium II iodide; reduction; single electron transfer; nitro group reduction; mechanistic study; bond cleavage; deoxygenation; additives; toluenesulfonyl deprotection; defluorination.;

   Sammanfattning : This thesis describes the development of methods using divalent samarium reagents in organic synthesis. The main focus is placed on functional group reductions, but reductive formation of carbon-carbon bonds has also been investigated. LÄS MER

5. 4. Carboligation using the aldol reaction : A comparison of stereoselectivity and methods

   Författare :Derar Al-Smadi; Mikael Widersten; Ulf Nilsson; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; aldol reaction; cinchonine; FSA enzyme; homologation reactions; phenylacetaldehyde derivatives; samarium diiodide.;

   Sammanfattning : The research summarized in this thesis focuses on synthesizing aldehyde and aldol compounds as substrates and products for the enzyme D-fructose-6-aldolase (FSA). Aldolases are important enzymes for the formation of carbon-carbon bonds in nature. LÄS MER

7. 5. Robust Multi-objective Optimization of Rare Earth Element Chromatography

   Författare :Hans-Kristian Knutson; Avdelningen för kemiteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Chromatography; Rare earth elements; Modeling; Multi-objective optimization; Robust optimization; Chromatography; Rare earth elements; Modeling; Multi-objective optimization; Robust optimization;

   Sammanfattning : Rare earth elements comprise the metallic elements known as lanthanides as well as scandium and yttrium. They are extensively used in modern technological industries and are considered as strategic commodities in many countries. LÄS MER