Sökning: "Saccharin"
Hittade 5 avhandlingar innehållade ordet Saccharin.
1. Modulating Sirtuin Activity - Design, Synthesis and Evaluation of Sirtuin 2 Inhibitors
Sammanfattning : Sirtuins (SIRTs) are NAD+-dependent lysine deacetylating enzymes targeting histones and a multitude of non-histone proteins. The SIRTs have been related to important cellular processes such as gene expression, cell proliferation, apoptosis and metabolism. They are proposed to be involved in the pathogenesis of e.g. LÄS MER
2. Engineering of metal microstructures : process-microstructure-property relationships for electrodeposits
Sammanfattning : The relationships between growth-conditions, topography and microstructure, and physical properties of electrochemically deposited copper, nickel and zinc-iron alloys were studied. Growth was investigated while systematically varying process parameters such as electrolyte chemistry, type and concentration of additives, current density, and mass transport. LÄS MER
3. Appetite regulating neuropeptides in alcohol addiction : focus on melanin concentrating hormone and its mch1-receptor
Sammanfattning : Current treatment options for alcohol use disorders are limited in number and have limited efficacy. It is therefore important to find new, more effective medications. LÄS MER
4. Fluorine-Free Phosphorus-Based Ionic Materials and Electrolytes
Sammanfattning : Due to the successful commercialization of lithium-ion batteries (LIBs), there is a growing interest in developing new battery materials with beneficial electrochemical properties. However, the uneven distribution of lithium resources and the low abundance of lithium in the earth crust are the main obstacles for further development and large-scale production of LIBs. LÄS MER
5. Maternal deprivation and mood stabilizing drugs : effects on rat brain NPY
Sammanfattning : Experiences of early adverse life events are more frequent among adult depressed patients than healthy subjects. Studies with non-human primates and rats show that maternal deprivation leads to changes in hypothalamic-pituitary adrenal (HPA)-axis activity/reactivity and increased levels of anxiety and alcohol preference. LÄS MER