Sökning: "SUMO"
Visar resultat 1 - 5 av 28 avhandlingar innehållade ordet SUMO.
1. THE ANGIOGENIC RESPONSE IN HYPOXIC HEART. Experimental studies in mice
Sammanfattning : Coronary artery disease is the leading cause of death in the western world today. Although induction of angiogenesis would appear to be an ideal therapeutic strategy, clinical trials of proangiogenic factors have proved disappointing. LÄS MER
2. On Transient Communication Outages among Collaborating Connected and Automated Vehicles
Sammanfattning : Recent advances in wireless technology facilitating Vehicle-to-Vehicle (V2V) communication have paved the way towards connected and more cooperative Intelligent Transportation Systems (ITSs), enhancing road safety and sustainability. Connected and Automated Vehicles (CAVs) can exchange information with one another and their surrounding infrastructure, thereby enabling cooperative automated maneuvering such as vehicle platooning. LÄS MER
3. Modulation of PDGF receptors function by posttranslational modifications
Sammanfattning : The platelet-derived growth factor receptors (PDGFRs) play important roles in multiple cellular processes including cell survival, cell growth and cell migration. Dysregulation of PDGFRs causes aberrant PDGF signaling, which leads to various diseases. LÄS MER
4. Expression, regulation and fuction of small ubiquitin-related modifier-1. Interaction with nuclear proteins in vivo
Sammanfattning : The small ubiquitin-related modifier-1 (SUMO-1) is a 101-amino acid, ~12 kDa protein that is 18% identical to ubiquitin. Posttranslational covalent tagging of proteins with SUMO-1 (SUMOylation) serves many functions. For example, regulation of protein stability and modulation of transcriptional activation. LÄS MER
5. The role of SUMO pathway in pathophsiology of skeletal muscle
Sammanfattning : Skeletal muscles are highly evolved and essential organs comprising 40 % of the total human body weight. They are essential in maintaining posture, energy metabolism, secrete hormones and act as central reserves for amino acids. LÄS MER