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Visar resultat 1 - 5 av 7 avhandlingar som matchar ovanstående sökkriterier.

1. 1. On the Role of Polyamines in Apoptosis

   Författare :Cecilia Hegardt; Bröstcancer-genetik; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; SSAT; DENSPM; spermine; polyamines; mitochondrial membrane potential; cytochrome c; caspase; flow cytometry; Jurkat cells; mouse thymocytes; thymus in vivo; programmed cell death; Dexamethasone-induced apoptosis; Fas-induced apoptosis; AdoMetDC; Cytology; oncology; cancerology; Cytologi; onkologi; cancer; Clinical biology; Klinisk biologi; Animal physiology; Djurfysiologi;

   Sammanfattning : Apoptosis is a kind of death that is best described as cellular suicide and it is important for normal tissue homeostasis. The process can be induced by a number of different stimuli and the dying cell goes through a defined pathway terminating in typical biochemical and morphological alterations of the cell. LÄS MER

3. 2. Development and application of advanced electron microscopy techniques for materials in biological systems

   Författare :Pernilla Nevsten; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; multiple-unit drug; EFTEM; EELS; cyanine dye; SSAT; cryo-TEM; virus; TEM; apoptosis; SEM; AFm; α-TCP; apatite; XEDS; TEM grid; microscopy supports;

   Sammanfattning : Theoretically, electron microscopy and scanning probe microscopy offer information on a scale beyond the optical microscope. However, the quality of the micrograph and the obtained information is limited by the sample preparation. LÄS MER

4. 3. Regulation of Polyamine Analogue-Induced Apoptosis in Human Breast Cancer Cells

   Författare :Martina Holst; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cancer; Animal physiology; Djurfysiologi; Pharmacological sciences; pharmacognosy; pharmacy; onkologi; Cytologi; cancerology; oncology; Cytochrome c; Cytology; Bcl-2; Mitochondrial respiration; Apoptosis; Human breast cancer cells; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi; Social medicine; Socialmedicin; samhällsmedicin; Mitochondria; Polyamine analogues;

   Sammanfattning : Apoptosis is a defined process for cells to commit suicide through a set of biochemical and morphological cell changes. Activated apoptotic signals converge on the mitochondria, leading to permeabilization of mitochondrial membranes and release of different apoptosis regulatory proteins into the cytosol. LÄS MER

5. 4. Gruppskillnader i Provresultat : uppgiftsinnehållets betydelse för resultatskillnader mellan män och kvinnor på prov i ordkunskap och allmänorientering

   Författare :Christina Stage; Umeå universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Test bias; item bias; content bias; sex bias; sex differences; vocabulary tests; tests on general knowledge;

   Sammanfattning : The present monograph deals with the problem of sex differences in test results from various angles. Initially, the aim was to investigate whether the use of test results in selection could be considered fair in spite of sex differences in test score averages. LÄS MER

7. 5. Effects of polyamine pool manipulation on genes expressed during the cell cycle

   Författare :Pia Berntsson; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Animal physiology; cyclin A; ODC; MCF-7; mitotic shake off; DENSPM; CHO; cDNA microarray; cell cycle; spermine; Djurfysiologi; AdoMetDC; 2D gel electrophoresis; polyamines; spermidine; putrescine;

   Sammanfattning : The polyamines - putrescine, spermidine and spermine - are polycations found within cells. They have been shown to be essential for optimal cell proliferation and cell survival. Cells maintain their polyamine levels in a well-regulated system involving biosynthesis, catabolism and uptake/excretion. LÄS MER