Sökning: "SRA - Molekylär biovetenskap"

Visar resultat 11 - 15 av 20 avhandlingar innehållade orden SRA - Molekylär biovetenskap.

  1. 11. Strategies for the Discovery of Carbohydrate-Active Enzymes from Environmental Bacteria

    Författare :Johan Larsbrink; Vincent Bulone; Harry Brumer; Birte Svensson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; CAZyme discovery; xyloglucan; polysaccharide-utilisation locus; microbiota; α-xylosidase; GH31; transglucosidase; human gut; SRA - Molekylär biovetenskap; SRA - Molecular Bioscience;

    Sammanfattning : The focus of this thesis is a comparative study of approaches in discovery of carbohydrate-active enzymes (CAZymes). CAZymes synthesise, bind to, and degrade all the multitude of carbohydrates found in nature. LÄS MER

  2. 12. An albumin-binding domain as a scaffold for bispecific affinity proteins

    Författare :Johan Nilvebrant; Sophia Hober; Andrew Bradbury; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; albumin-binding domain; bispecific; albumin; affinity protein; phage display; staphylococcal display; orthogonal affinity purification; TNF-alpha; ErbB2; ErbB3; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

    Sammanfattning : Protein engineering and in vitro selection systems are powerful methods to generate binding proteins. In nature, antibodies are the primary affinity proteins and their usefulness has led to a widespread use both in basic and applied research. LÄS MER

  3. 13. Quality assessment of protein models

    Författare :Arjun Ray; Erik Lindahl; Bengt Persson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

    Sammanfattning : Proteins are crucial for all living organisms and they are involved in many different processes. The function of a protein is tightly coupled to its structure, yet to determine the structure experimentally is both non-trivial and expensive. LÄS MER

  4. 14. Computational Modeling of Cancer Progression

    Författare :Hossein Shahrabi Farahani; Jens Lagergren; Niko Beerenwinkel; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cancer progression; Bayesian networks; microRNA editing; SRA - Molekylär biovetenskap; SRA - Molecular Bioscience;

    Sammanfattning : Cancer is a multi-stage process resulting from accumulation of genetic mutations. Data obtained from assaying a tumor only contains the set of mutations in the tumor and lacks information about their temporal order. Learning the chronological order of the genetic mutations is an important step towards understanding the disease. LÄS MER

  5. 15. Theoretical Characterization of Functional Molecular Materials

    Författare :Xiuneng Song; Yi Luo; Mauro Stener; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; first-principles; soft X-ray spectroscopy; endohedral fullerene; fullerene derivatives; self-assembled monolayers; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

    Sammanfattning : Nowadays, material, energy and information technologies are three pillar industries. The materials that have close relation with our life have also been the foundation for the development of energy and information technologies. LÄS MER