Sökning: "SR proteins"

Visar resultat 6 - 10 av 27 avhandlingar innehållade orden SR proteins.

  1. 6. Functional Characterization of the Evolutionarily Conserved Adenoviral Proteins L4-22K and L4-33K

    Författare :Sara Östberg; Göran Akusjärvi; Stefan Schwartz; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; L4-22K; L4-33K; RNA; splicing; adenovirus; nuclear localization; replication; transcription; evolution; SR protein; MLP; promoter; E1A; serotypes;

    Sammanfattning : Regulation of adenoviral gene expression is a complex process directed by viral proteins controlling a multitude of different activities at distinct phases of the virus life cycle. This thesis discusses adenoviral regulation of transcription and splicing by two proteins expressed at the late phase: L4-22K and L4-33K. LÄS MER

  3. 7. Molecular structure and intracellular location of five RNA : associated proteins in the salivary glands of the dipteran Chironomus tentans

    Författare :Sun Xin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :hnRNPs; RNA-binding domains; shuttling proteins; non-shuttling proteins; nucleo-cytoplasmic transport; SR proteins;

    Sammanfattning : The structure and intracellular flow of specific RNA-associated proteins have been characterized in the salivary gland cells in the dipteran Chironomus tentans. These cells contain four polytene chromosomes (I-IV), two of which harbour a nucleolus. LÄS MER

  4. 8. Regulation of HIV-1 mRNA Processing by Cellular Splicing Factors

    Författare :Anna Tranell; Stefan Schwartz; Göran Akusjärvi; Ingemar Ernberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; SR protein; SRp55; SFRS6; splicing; indole derivative; Medical Virology; Medicinsk virologi;

    Sammanfattning : According to UNAIDS there were 34 million people living with human immunodeficiency virus (HIV) infection at the end of 2010. HIV is the causative agent of acquired immunodeficiency syndrome (AIDS) and the number of people dying of AIDS-related causes at the end of 2010 was 1.8 million. LÄS MER

  5. 9. Regulation of adenovirus alternative pre-mRNA splicing : Functional characterization of exonic and intronic splicing enhancer elements

    Författare :Bai-Gong Yue; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; adenovirus; pre-mRNA splicing; splicing enhancer; MLTU; L1; SR protein; ASF SF2; E. coli; phosphorylation; dephosphorylation; Biokemi; Biochemistry; Biokemi; mikrobiologi; Microbiology;

    Sammanfattning : Pre-mRNA splicing and alternative pre-mRNA splicing are key regulatory steps controlling geneexpression in higher eukaryotes. The work in this thesis was focused on a characterization of thesignificance of exonic and intronic splicing enhancer elements for pre-mRNA splicing. LÄS MER

  7. 10. Defining the Role of GGTase-I in the Development of Rheumatoid Arthritis and Atherosclerosis

    Författare :Omar M. Khan; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GGTase-I; Inflammation; RHO proteins; Rheumatoid Arthritis; Atherosclerosis;

    Sammanfattning : RHO family proteins control cell movement and intracellular signaling by cycling between active GTP-bound and inactive GDP-bound states. Aberrant signaling of RHO GTPases has been implicated in many diseases including cancer and inflammation. LÄS MER