Sökning: "SPR systems"

Visar resultat 1 - 5 av 17 avhandlingar innehållade orden SPR systems.

  1. 1. Surface Modifications for Biointerfaces - Supported Lipid Bilayers and some Aspects of Microcontact Printing

    Författare :Karin Glasmästar; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; QCM-D; PDMS; cell attachment; supported lipid bilayer; microcontact printing; SPR; ToF-SIMS; protein adsorption; formation kinetics; XPS;

    Sammanfattning : Biointerfaces engage several disciplines: physics, materials science, chemistry, biology and medicine. They are found on the surfaces of implants, tubes and tanks in the food industry or on the hull of a boat. In this work, model surfaces aimed for contact with biological systems were studied. LÄS MER

  3. 2. On the Formation of Supported Phospholipid Bilayers

    Författare :Erik Reimhult; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; vesicle adsorption; formation kinetics; SPR; QCM-D; SPB; AFM; supported lipid bilayer; supported membrane; liposome;

    Sammanfattning : Lipid bilayers are a central component of both the structure and function of biological membranes, like the one surrounding cells of living organisms. Since the lipid bilayer provides a host matrix for membrane proteins, which perform many of the specialized tasks in cells like energy, signal and material transduction, researchers have tried to develop artificial model membranes to study a variety of membrane protein functions. LÄS MER

  4. 3. Multiparametric Optical Characterization of Biological Nanoparticles using Evanescent Field Sensing

    Författare :Mattias Sjöberg; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; protein corona; single-particle; liposomes; SPR; lipid nanoparticles; Waveguide scattering microscopy; label-free; mass quantification.;

    Sammanfattning : In light of the increasingly realized dependence of many biological functions on nanoscopic supramolecular assemblies, also including novel biotechnological applications, there is a need for advanced analysis methods capable of accurately quantifying different characteristics of these elusive entities. The prime aim of this thesis is the development and utilization of surface-based bioanalytical sensing methods for quantitative characterization of biological nanoparticles. LÄS MER

  5. 4. Novel factors affecting clearance of triacylglycerol-rich lipoproteins from blood

    Författare :Stefan K Nilsson; Gunilla Olivecrona; Aivar Lookene; Ko Willems van Dijk; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lipoprotein; triacylglycerol; apolipoprotein A-V; ANGPTL; Cardiovascular medicine; Kardiovaskulär medicin; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : Apolipoprotein (apo) A-V is the most recently discovered member of a protein family responsible for the structure and metabolic fate of plasma lipoproteins. While most of the apolipoproteins are well characterized with regard to structure, interactions and function, the role of apoA-V is not well understood. LÄS MER

  7. 5. Development and Validation of Methods for Characterization of Multi-Component Systems in Preparative LC

    Författare :Robert Arnell; Torgny Fornstedt; Andreas Seidel-Morgenstern; Uppsala universitet; []
    Nyckelord :Analytical chemistry; Liquid chromatography; Preparative LC; Chiral LC; Multi-component LC; Adsorption isotherm; Tracer-pulse method; Inverse method; Inverse method on plateaus; Peak deformations; Chiral drug-protein interactions; Analytisk kemi;

    Sammanfattning : This thesis concerns the development and validation of methods for characterization of multi-component preparative LC systems. Measurements of competitive adsorption isotherms are performed to gain detailed information about the interactions inside the chromatography column. LÄS MER