Sökning: "SPN"

Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet SPN.

  1. 1. Striatal adaptations in experimental parkinsonism and L-DOPA-induced dyskinesia

    Författare :Tim Fieblinger; Basala gangliernas patofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Striatum; Parkinson’s disease; L-DOPA-induced dyskinesia; ERK1 2; mGluR5; homeostatic plasticity; SPN; 2‑Photon microscopy;

    Sammanfattning : Parkinson’s disease (PD) is a neurodegenerative disorder, characterized by the loss of dopamine (DA) producing neurons in the substantia nigra pars compacta (SNc), resulting in typical motor symptoms. DA replacement with L-DOPA is the standard therapy for PD. LÄS MER

  3. 2. Antibiotic resistance and pathogenesis of Streptococci with focus on Group A Streptococci

    Författare :Feiruz Alamiri; Malmö Experimentell infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibiotika resistens; Bröstmjölk; Luftvägsinfektioner; Biofilm bildning; Internalisering; Persistens; HAMLET; Streptokocker; kolonisering; Streptococcus pneumoniae; biofilm formation; Internalisation; Persistence; Antibiotic resistance; Streptococcus pyogenes; Streptococcus agalactiae; HAMLET; Breast milk; Proteome; Virulence factors; Colonization;

    Sammanfattning : Multi-drug resistant (MDR) infections remain the leading cause of death worldwide. MDR infections caused by Streptococcus pneumoniae (Spn), Streptococcus pyogenes (GAS) and Streptococcus agalactiae (GBS) are considered global threats to human health due to increased spread of antibiotic resistance and limited treatment options. LÄS MER

  4. 3. Computational Modelling and Topological Analysis of the striatal microcircuitry in health and Parkinson's disease

    Författare :Ilaria Carannante; Jeanette Hellgren Kotaleski; Alexander Kozlov; Sean Hill; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Datalogi; Computer Science;

    Sammanfattning : The basal ganglia are evolutionary conserved nuclei located at the base of the forebrain. They are a central hub in the control of motion and their dysfunctions lead to a variety of movement related disorders, including Parkinson's disease (PD).The largest nucleus and main input stage of the basal ganglia is the striatum. LÄS MER

  5. 4. Particulate Formation in Gasoline Direct Injection Engines

    Författare :Sreelekha Etikyala; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; PM; Volatileorganic compounds; Gasoline Direct Injection; Particulate Number; Alternate fuels;

    Sammanfattning : Gasoline direct injection (GDI) engines are facing a great challenge because of the need to comply with increasingly stringent emission regulations while improving fuel economy. GDI engines are popularly known for their high fuel efficiency (by the standards of gasoline engines) and low emissions, enabling higher compression ratios and thus increased volumetric efficiency. LÄS MER

  7. 5. On striatum in silico

    Författare :Johanna Frost Nylén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The basal ganglia are a collection of subcortical nuclei involved in movement and action selection. The striatum is the main input nucleus with extensive projections from the cortex and thalamus, and dopaminergic projections from SNc and VTA. LÄS MER