Sökning: "SPION nanoparticles"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden SPION nanoparticles.

  1. 1. Nanoparticles : Engineering, Assembly, and Biomedical Applications

    Författare :Do Kyung Kim; KTH; []
    Nyckelord :nanoparticle; superparamagnetism; self assembly; ;

    Sammanfattning : This thesis deals with novel aspects through Nanotechnologyof"bottom-up"and"top-down"strategies in combination with Biotechnology as aninterdisciplinary study. The feasibility of chemically tailoredsuperparamagnetic iron oxide nanoparticles (SPION) forin-vivobiomedical applications has beendemonstrated. LÄS MER

  2. 2. Design of Functional Polymeric Nanoparticles for Biomedical Applications

    Författare :Heba Asem; Eva Malmström; Tim Bowden; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biodegradable polymers; SPION; PISA; RAFT; nanoparticles; drug delivery; cytotoxicity; MRI; in vivo fluorescence imaging; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : Most of the devastating diseases such as cancer are relatively incurable and have high risks of relapse. Therefore, persistent endeavors have been devoted to improve patient survival rate and quality of life. LÄS MER

  3. 3. Nanoparticles for multifunctional drug delivery systems

    Författare :Jian Qin; Mamoun Muhammed; Paavo K J Kinnunen; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; drug delivery; stimuli-sensitive; SPION; PLLA; PNIPAAm; gold; MRI; cytotoxicity; Pluronic; phase transfer; Materials chemistry; Materialkemi;

    Sammanfattning : Multifunctional drug delivery systems incorporated with stimuli-sensitive drug release, magnetic nanoparticles and magnetic resonance (MR) T2 contrast agents is attracting increasing attention recently. In this thesis, works on polymer nanospheres response to temperature change, superparamagnetic iron oxide nanoparticles (SPION)/polymeric composite materials for MR imaging contrast agents are summarized. LÄS MER

  4. 4. Ultrasound Contrast Agents Loaded with Magnetic Nanoparticles : Acoustic and Mechanical Characterization

    Författare :VeeraVenkata Satyanarayana Kothapalli; Lars-Åke Brodin; Jan Engvall; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Ultrasound contrast agents; SPION nanoparticles; harmonic oscillation; backscattering power; attenuation coefficient; phase velocity; nonlinear equation of motion;

    Sammanfattning : The current methodologies in body scanning diagnostic uses different simultaneous imaging modalities like Ultrasound (US), magnetic resonance imaging (MRI), single photon emission tomography (SPECT) and positron emission tomography (PET). The field requires combination of different modalities for effective use in clinical diagnostics. LÄS MER

  5. 5. Superparamagnetic iron oxide nanoparticles (SPIONs) as a multimodality imaging probe for sentinel nodes : Design and Preclinical Evaluation

    Författare :Renata Madru; Lund Medicinsk strålningsfysik; []
    Nyckelord :iron oxide; nanoparticles; SPIONs; PET-MRI; SPECT-MRI; SPECT-MRI- optical imaging; sentinel lymph node; SNL;

    Sammanfattning : Breast cancer and malignant melanoma disseminate through the lymphatic system and the first metastases arise in one or two regional, sentinel lymph nodes (SLNs) draining the primary tumour site. Therefore, identification and characterization of the SLNs is of major importance for cancer staging and for choice of therapy in patients. LÄS MER