Sökning: "SPF"

Visar resultat 16 - 19 av 19 avhandlingar innehållade ordet SPF.

  1. 16. Alterations in the PI3K/AKT Signaling Pathway and Response to Adjuvant Treatment in Breast Cancer

    Författare :Gizeh Pérez-Tenorio; Olle Stål; Anne Lykkesfeldt; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Onkologi;

    Sammanfattning : (PI3K)/AKT signaling pathway could be a cause of therapeutic resistance in breast cancer. The PI3K/AKT pathway controls cell proliferation, cell growth and survival, and its members include oncogenes and tumor suppressor genes. Alterations in this pathway are frequent in cancer. LÄS MER

  3. 17. Gut microbes and the developing brain

    Författare :Tim Arentsen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The discovery that commensal gut microbiota can influence host development and physiology beyond the gastrointestinal (GI) tract has triggered a paradigm shift in our conceptualization of the origin of human diseases. A growing body of preclinical research has demonstrated that gut microbiota exert a modulatory role on the development and function of brain circuits involved in motor control, emotion and cognition. LÄS MER

  4. 18. Investigation of T cell driven arthritis induced by mannan in ZAP70 mutated SKG mice

    Författare :Simon Guérard; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Autoimmune diseases are particularly challenging to study in human due to their complex multifactorial nature. In rheumatoid arthritis (RA), self-reactivity directed against joints leads to pain, tissue destruction and eventually invalidity if left untreated. LÄS MER

  5. 19. Livsplats, välbefinnande och kontrast : Väl- och illabefinnandets livsplatser, ur objekt-, subjekt- och processperspektiv

    Författare :Nicklas Skillnäs; Bengt Richt; Gunilla Tegern; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : The purpose of this thesis is to develop a conceptual and theoretical understanding of place, with particular emphasis on places of wellbeing and illbeing, by taking account of life as a process. The thesis rests on empirical ground and takes off from the lack of conceptual and theoretical understanding and the neglected relationship between wellbeing, illbeing, place and lived lives in similar research. LÄS MER