Sökning: "SOX10"

Visar resultat 11 - 15 av 16 avhandlingar innehållade ordet SOX10.

  1. 11. Role of transcription factors in sensory neuron specification

    Författare :Andreas Montelius; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The interface between our mind and the internal and external environments is the peripheral nervous system. A range of different sensory neuron subtypes detects cold, heat, pain, touch, and other stimuli. LÄS MER

  3. 12. Repair and Reconstruction of Peripheral Nerve Injuries. Treatment with G-CSF and Stromal Vascular Fraction

    Författare :Hanna Frost; Malmö Handkirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; peripheral nerve injuries; nerve regeneration; reconstructive surgical procedures; diabetes mellitus; rat sciatic nerve; granulocyte colony-stimulating factor; stromal vascular fraction; electrospinning; rats; Schwann cells;

    Sammanfattning : While surgery is a cornerstone in treatment of peripheral nerve injuries, it is not a comprehensive approach, and outcome is unsatisfactory, especially sensory function. The present aim was to translate recent findings about stem- and progenitor cells to improve regenerative outcome, where the cells have to be autologous, available within the same surgical procedure, and minimally manipulated. LÄS MER

  4. 13. On molecular mechanisms of neural differentiation and forebrain development

    Författare :Erik Södersten; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Telencephalic development is an extraordinary complex process where neural structures of highly diverse cell compositions emerge as the result of multiple developmental strategies imposing tight regulation, balance and timing of gene expression. Embryonic telencephalic neural stem cells (NSCs) can form the major cell types found in the telencephalon, and are thus an excellent model for studying transcriptional control of lineage choice mechanisms in CNS development. LÄS MER

  5. 14. Single-cell analysis of mammalian cardiogenesis elucidating an essential role of outflow tract progenitors

    Författare :Chikai Zhou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The heart is the first organ to form and start to function during mammalian embryogenesis. This complex organ system is constructed by a diverse set of cell types, involving mesodermal precursors and heart progenitors, at the earliest embryonic stages. LÄS MER

  7. 15. Neurons and glia in the peripheral nervous system : interactions in health and disease

    Författare :Filipa Bouçanova; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The peripheral nervous system (PNS) is composed of nerves and ganglia that connect the brain and the spinal cord (the central nervous system, CNS) to the outside world. The nerves contain the extensions (axons) of both sensory and motor neurons, which allow us to detect and respond to different stimuli. LÄS MER