Sökning: "SNPs"
Visar resultat 11 - 15 av 319 avhandlingar innehållade ordet SNPs.
11. Evidence for adaptive variation at the genes coding for cytosolic phosphoglucose isomerase (PGIC) in Festuca ovina L
Sammanfattning : The gene (Pgi) encoding the enzyme phosphoglucose isomerase (PGI) which plays a central role in the main pathways of carbon metabolism has been shown to be of adaptive significance in a wide range of different species. Earlier studies of enzyme electromorph variation in the grass Festuca ovina suggest that variation in cytosolic PGI (PGIC) may be involved in the adaptive response of F. LÄS MER
12. Large-scale releases of native species : the mallard as a predictive model system
Sammanfattning : Human alteration of natural systems, and its consequences are of great concern and the impact on global ecosystems is one of the biggest threats that biodiversity stands before. Translocations of invasive species, as well as intraspecific contingents with non-native genotypes, whether they are deliberate or unintentional, are one such alteration and its consequences are continuously being assessed. LÄS MER
13. Molecular Epidemiology of Breast Cancer
Sammanfattning : Hereditary breast cancer constitutes a considerable fraction of the total number of breast cancer cases occurring each year. Up until recently very few breast cancer predisposing genes were known, but many new common polymorphisms contributing to increased cancer susceptibility are continuously being identified. LÄS MER
14. Using SNPs to study complex genetic disease : a population and evolutionary genetics perspective
Sammanfattning : Associating genes to complex genetic diseases has proven more difficult than anticipated. Many genetic variants contribute small effects towards an individual's disease predisposition in polygenic diseases, and this biological complexity requires new methods of analysis. LÄS MER
15. Genetic variation in genes involved in Abeta-degradation in Alzheimer disease
Sammanfattning : Alzheimer disease (AD) is a neurodegenerative disorder that causes dementia among mainly elderly people and is increasing in prevalence in industrialized societies from 1 to 3 % in 60-65 year-olds to as much as 50 % by age 95. This disease is complex. Multiple genes are involved, and they potentially affect each other. LÄS MER