Sökning: "SF-1"

Hittade 4 avhandlingar innehållade ordet SF-1.

  1. 1. Developmental and reproductive regulation of NR5A genes in teleosts

    Författare :Jonas von Hofsten; Per-Erik Olsson; Gregory Kelly; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; FTZ-F1; NR5A; zebrafish; teleost; arctic char; SF-1; LRH-1; fushi tarazu; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : In mammals sex chromosomes direct and initiate the development of male and female gonads and subsequently secondary sex characteristics. In most vertebrates each individual is pre-destined to either become male or female. LÄS MER

  3. 2. Transcriptional regulation by the nuclear receptors steroidogenic factor-1 and liver receptor homologue-1

    Författare :Anna Ehrlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Steroidogenic Factor-1 (SF-1) and Liver Receptor Homologue-1 (LRH-1) are transcription factors belonging to the nuclear receptor (NR) family. In the adrenal cortex and gonads, SF-1 governs the expression of multiple enzymes and transporters required for converting cholesterol to steroid hormones. LÄS MER

  4. 3. Identification and characterization of stem Leydig cells in the testis

    Författare :Luise Landreh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In the testis, several cell types are needed to ensure male fertility, among them the testosterone-producing Leydig cells. Testosterone supports the maturation of sperm and maintains the male phenotype. Functional Leydig cells are therefore required to prevent testicular malfunction. LÄS MER

  5. 4. Novel genes in gonadal development

    Författare :Virpi Töhönen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mammalian sex determination and differentiation can be divided into three major steps. In the first step, which occurs at fertilisation, the genetic sex is established, XX or XY. In the second step, development of the indifferent gonad into either an ovary or a testis takes place. LÄS MER