Sökning: "SF Failure"
Visar resultat 1 - 5 av 24 avhandlingar innehållade orden SF Failure.
1. Heart failure : biomarker effect and influence on quality of life
Sammanfattning : Background and aims: Heart failure (HF) is a life threatening condition and optimal handling is necessary to reduce risk of therapy failure. The aims of this thesis were: (Paper I) to examine whether BNP (B-type natriuretic peptide)-guided HF treatment improves morbidity and mortality when compared with HF therapy implemented by a treating physician at sites experienced in managing patients with HF according to guidelines; (Paper II) to investigate how to define a responder regarding optimal cut-off level of BNP to predict death, need for hospitalisation, and worsening HF and to determine the optimal time to apply the chosen cut-off value; (Paper III) to evaluate how Health-Related Quality of Life (HR-QoL) is influenced by natriuretic peptide guiding and to study how HR-QoL is affected in responders compared to non-responders; (Paper IV) to evaluate the impact of patient age on clinical outcomes, and to evaluate the impact of duration of the HF disease on outcomes and the impact of age and HF duration on BNP concentration. LÄS MER
2. Radiobiological end-points for the theoretical evaluation of the effectiveness of carbon ions and photons in treating tumours with dynamic hypoxia
Sammanfattning : Tumours are characterised by unorganised vasculature, which often results in hypoxic regions. Hypoxia is a common cause for photon radiotherapy (RT) treatment failure, as hypoxic cells require up to 2-3 times higher doses compared to well-oxygenated cells for the same effect in terms of cell kill. LÄS MER
3. Climate Change: Models, Metrics and Meaning Making
Sammanfattning : This thesis, combining research in climate science and educational science, investigates different aspects of climate knowledge. It consists of five papers and covers three major topics: emission metrics, public understanding of atmospheric CO2 accumulation, and spatial modelling of natural resource use. LÄS MER
4. Health‐related quality of life, depression, sleep and breathing disorders in the elderly : With focus on those with impaired systolic function/heart failure
Sammanfattning : The overall aim of this thesis was to describe the prevalence of depressive symptoms, sleep disordered breathing (SDB) and sleep complaints, as well as to investigate the prognostic value of health-related quality of life (Hr-QoL) and depressive symptoms on mortality in an elderly community living population with a focus on those with impaired systolic function/heart failure (HF). Descriptive, prognostic and explorative study designs were used to examine if a single question about global perceived health (GPH) is associated with the domains of Hr-QoL as assessed by the SF-36 (I), as well as to evaluate whether GPH provided prognostic information concerning cardiovascular mortality (II). LÄS MER
5. HEALTH RELATED QUALITY OF LIFE AMONG PERSONS 65 YEARS OR OLDER WITH CHRONIC HEART FAILURE: AN EMPIRICAL AND METHODOLOGICAL STUDY
Sammanfattning : The aim of this thesis was to empirically and methodologically investigate health related quality of life (HRQoL) among persons 65 years or older with chronic heart failure. The design was cross-sectional and the sample was recruited from a southeast region of Sweden. LÄS MER
