Sökning: "SEQUENCE"

Visar resultat 21 - 25 av 2869 avhandlingar innehållade ordet SEQUENCE.

1. 21. Algorithms for building and evaluating multiple sequence alignments

   Författare :Timo Lassmann; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Bioinformatics; sequence analysis; sequence alignment; multiple sequence alignment;

   Sammanfattning : The alignment of biological sequences is crucial for the transfer of annotation from model organisms to humans. Pairwise alignment of sequences can reveal homology while multiple alignments are used to characterize protein families and elucidate their evolutionary history. LÄS MER

3. 22. Program Matters : From Drawing to Code

   Författare :Pablo Miranda Carranza; Katja Grillner; Daniel Koch; Charlie Gulström Hughes; Molly Wright Steenson; KTH; []
   Nyckelord :HUMANIORA; HUMANITIES; program; algorithm; code; drawing; geometry; notation; score; literacy; writing systems; diagram; formalism; sequence; cybernetics; materiality; research programme; archeological; archive; discourse analysis; practice-based; artefact; bricolage; Architecture; Arkitektur;

   Sammanfattning : Whether on paper, on site or mediating between both, means for reading and writing geometry have been central to architecture: the use of compasses and rulers, strings, pins, stakes or plumb-lines enabled the analysis and reproduction of congruent figures on different surfaces since antiquity, and from the renaissance onwards, the consistent planar representation of three-dimensional shapes by means of projective geometry. Tacitly through practice, or explicitly encoded in classical geometry, the operational syntaxes of drawing instruments, real or imaginary, have determined the geometric literacies regulating the production and instruction of architecture. LÄS MER

4. 23. Experimental and computational exploration of enzyme sequence space

   Författare :Elzbieta Rembeza; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; high-throughput-screening; protein annotation; enzyme discovery; enzyme sequence space; oxidases;

   Sammanfattning : Millions of enzymes with desirable features or new exciting activities can be found in organisms occupying diverse niches all around the earth. However, enzyme studies tend to be biased towards characterisation of representatives from eukaryotes, model organisms, or disease-causing bacteria. LÄS MER

5. 24. Engineering enzymes towards biotherapeutic applications using ancestral sequence reconstruction

   Författare :Natalie Hendrikse; Per-Olof Syrén; Johan Rockberg; Erik Nordling; Reinhard Sterner; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; enzyme engineering; enzyme evolution; ancestral sequence reconstruction; therapeutic enzymes; terpene cyclases; ammonia-lyases; sulfatases; lysosomal enzymes; Kemi; Chemistry;

   Sammanfattning : Enzymes are versatile biocatalysts that fulfill essential functions in all forms of life and, therefore, play an important role in health and disease. One specific application of enzymes in life science is their use as biopharmaceuticals, which typically benefits from high catalytic activity and stability. LÄS MER

7. 25. Characterization of protein families, sequence patterns, and functional annotations in large data sets

   Författare :Anders Bresell; Bengt Persson; Inge Jonassen; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioinformatics; sequence analysis; patterns; protein families; Bioinformatics; Bioinformatik;

   Sammanfattning : Bioinformatics involves storing, analyzing and making predictions on massive amounts of protein and nucleotide sequence data. The thesis consists of six papers and is focused on proteins. LÄS MER