Sökning: "SE Bonn"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden SE Bonn.

  1. 1. Experimental and computational investigation of affinity and selectivity factors in CYP2D6 and CYP3A4 mediated metabolism

    Författare :Britta Bonn; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cytochrome P450; in vitro metabolism; biotransformation; computational modeling; drug design;

    Sammanfattning : The assessment of ADME properties and metabolic behavior of a drug is central in drug discovery and drug design. The main target for studies of metabolic properties is the Cytochrome P450 (CYP), which is responsible for the metabolism of a majority of drugs on the market and consequently also involved in many drug-drug interactions. LÄS MER

  3. 2. Physical activity, body mass index and prostate cancer : studies of risk, progression and mortality

    Författare :Stephanie Bonn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prostate cancer is the most common cancer among men in developed countries, but it is still unclear what causes the disease. Body mass index (BMI) and physical activity are modifiable lifestyle factors with the potential to influence the development and progression of prostate tumors and may provide alternative strategies for reducing both prostate cancer incidence and mortality. LÄS MER

  4. 3. Improved Techniques for Sampling and Sample Introduction in Gas Chromatography

    Författare :Jonas Bonn; Johan Roeraade; Åsa Emmer; Mikael Hedenqvist; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Gaskromatografi; Provupparbetning; Provintroduktion; Analytical chemistry; Analytisk kemi;

    Sammanfattning : Sampling and sample introduction are two key steps in quantitative gas chromatography. In this thesis, a development of a previously described sampling technique as well as a novel concept for sample introduction in gas chromatography are presented. The thesis is based on two papers. LÄS MER

  5. 4. A la Recherche d’El Djezaïr. Postmodernisme et postcolonialisme dans deux romans algériens : L’Amour, la fantasia et L’Honneur de la tribu

    Författare :Stella Annani; Charles Bonn; Stockholms universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; French; franska;

    Sammanfattning : .... LÄS MER

  7. 5. Supporting healthy movement behaviours in people with metabolic risk, prediabetes, or type 2 diabetes in primary health care

    Författare :Kristina Larsson; Maria Hagströmer; Jenny Rossen; Unn-Britt Johansson; Åsa Norman; Stephanie Bonn; Sophiahemmet Högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The overall aim of this thesis was to investigate if a pedometer-based intervention inthe primary health care setting can support people with prediabetes or type 2 diabetestowards healthier movement behaviours. Moreover, health care professionals’experiences of supporting people with metabolic risk factors to increase theirphysical activity were explored. LÄS MER